KEGG   DRUG: D01366Help
Entry
D01366                      Drug                                   

Name
Bezafibrate (JP16/USAN/INN);
Bezatol SR (TN)
Formula
C19H20ClNO4
Exact mass
361.1081
Mol weight
361.8194
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihyperlipoproteinemic [DS:H00154 H00155 H00156 H00157]
Remark
Therapeutic category: 
ATC code: 
Target
peroxisome proliferator-activated receptor (PPAR) alpha agonist [HSA:5465] [KO:K07294]
  Pathway
hsa03320  PPAR signaling pathway
hsa04920  Adipocytokine signaling pathway  
 
Interaction
Drug interaction
Structure map
Peroxisome proliferator-activated receptor (PPAR) agonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AB Fibrates
     C10AB02 Bezafibrate
      D01366  Bezafibrate (JP16/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   218  Hyperlipidemia agents
    2183  Clofibrates
     D01366  Bezafibrate (JP16/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    peroxisome proliferator-activated receptor (PPAR) alpha
     Bezafibrate
      D01366  Bezafibrate (JP16/USAN/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01366  Bezafibrate
  D01366  Bezafibrate sustained release tablets
BRITE hierarchy
Other DBs
CAS: 
41859-67-0
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C8x C    20.0827  -19.2413
            2   C8y C    20.0827  -20.6407
            3   C8x C    21.2722  -21.3404
            4   C8x C    22.5316  -20.6407
            5   C8y C    22.5316  -19.2413
            6   C8x C    21.2722  -18.5416
            7   X   Cl   18.8932  -21.3404
            8   C5a C    23.7211  -18.5416
            9   N1b N    24.9106  -19.2413
            10  O5a O    23.7211  -17.1422
            11  C1b C    26.1701  -18.5416
            12  C1b C    27.3596  -19.2413
            13  C8y C    28.5490  -18.5416
            14  C8x C    29.8085  -19.2413
            15  C8x C    30.9980  -18.5416
            16  C8y C    30.9980  -17.1422
            17  C8x C    29.8085  -16.4425
            18  C8x C    28.5490  -17.1422
            19  O2a O    32.1875  -16.4425
            20  C1d C    33.4469  -17.1422
            21  C6a C    34.6364  -16.4425
            22  O6a O    35.8259  -17.1422
            23  O6a O    34.6364  -15.0431
            24  C1a C    32.7472  -18.3541
            25  C1a C    34.1466  -18.3541
BOND        26
            1     6   1 1
            2    12  13 1
            3     2   7 1
            4     1   2 2
            5     5   8 1
            6     2   3 1
            7    13  14 2
            8    14  15 1
            9    15  16 2
            10   16  17 1
            11   17  18 2
            12   18  13 1
            13    8   9 1
            14   16  19 1
            15    3   4 2
            16   19  20 1
            17    8  10 2
            18   20  21 1
            19    4   5 1
            20   21  22 1
            21    9  11 1
            22   21  23 2
            23    5   6 2
            24   11  12 1
            25   20  24 1
            26   20  25 1

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