KEGG   DRUG: BezafibrateHelp
Entry
D01366                      Drug                                   

Name
Bezafibrate (JP17/USAN/INN);
Bezatol SR (TN)
Formula
C19H20ClNO4
Exact mass
361.1081
Mol weight
361.8194
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01946  Hypolipidemic agent
  DG01547  Fibrates
Other
 DG01733  PPAR agonist
  DG01547  Fibrates
Remark
Therapeutic category: 
ATC code: 
Activity
Antihyperlipidemic, Triglyceride synthesis inhibitor, Peroxisome proliferator-activated receptor (PPAR) alpha agonist
Comment
Clofibrate derivative
Target
NR1C1 (PPARA) [HSA:5465] [KO:K07294]
  Pathway
PPAR signaling pathway
Adipocytokine signaling pathway
Interaction
Drug interaction
Structure map
Peroxisome proliferator-activated receptor (PPAR) agonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AB Fibrates
     C10AB02 Bezafibrate
      D01366  Bezafibrate (JP17/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   218  Hyperlipidemia agents
    2183  Clofibrates
     D01366  Bezafibrate (JP17/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    peroxisome proliferator-activated receptor (PPAR) alpha
     Bezafibrate
      D01366  Bezafibrate (JP17/USAN/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01366  Bezafibrate
  D01366  Bezafibrate sustained release tablets
Hypolipidemic agents [br08365.html]
 D01366
BRITE hierarchy
Other DBs
CAS: 
41859-67-0
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C8x C    20.0827  -19.2413
            2   C8y C    20.0827  -20.6407
            3   C8x C    21.2722  -21.3404
            4   C8x C    22.5316  -20.6407
            5   C8y C    22.5316  -19.2413
            6   C8x C    21.2722  -18.5416
            7   X   Cl   18.8932  -21.3404
            8   C5a C    23.7211  -18.5416
            9   N1b N    24.9106  -19.2413
            10  O5a O    23.7211  -17.1422
            11  C1b C    26.1701  -18.5416
            12  C1b C    27.3596  -19.2413
            13  C8y C    28.5490  -18.5416
            14  C8x C    29.8085  -19.2413
            15  C8x C    30.9980  -18.5416
            16  C8y C    30.9980  -17.1422
            17  C8x C    29.8085  -16.4425
            18  C8x C    28.5490  -17.1422
            19  O2a O    32.1875  -16.4425
            20  C1d C    33.4469  -17.1422
            21  C6a C    34.6364  -16.4425
            22  O6a O    35.8259  -17.1422
            23  O6a O    34.6364  -15.0431
            24  C1a C    32.7472  -18.3541
            25  C1a C    34.1466  -18.3541
BOND        26
            1     6   1 1
            2    12  13 1
            3     2   7 1
            4     1   2 2
            5     5   8 1
            6     2   3 1
            7    13  14 2
            8    14  15 1
            9    15  16 2
            10   16  17 1
            11   17  18 2
            12   18  13 1
            13    8   9 1
            14   16  19 1
            15    3   4 2
            16   19  20 1
            17    8  10 2
            18   20  21 1
            19    4   5 1
            20   21  22 1
            21    9  11 1
            22   21  23 2
            23    5   6 2
            24   11  12 1
            25   20  24 1
            26   20  25 1

» Japanese version   » Back

DBGET integrated database retrieval system