KEGG   DRUG: D01369Help
Entry
D01369                      Drug                                   

Name
Bevantolol hydrochloride (JAN/USAN);
Calvan (TN);
Vantol (TN)
Formula
C20H27NO4. HCl
Exact mass
381.1707
Mol weight
381.8936
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-anginal;
Antihypertensive;
Cardiac depressant [anti-arrythmic]
Remark
Therapeutic category: 
ATC code: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
beta-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB06 Bevantolol
      D01369  Bevantolol hydrochloride (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D01369  Bevantolol hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Bevantolol
      D01369  Bevantolol hydrochloride (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
42864-78-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C8y C    18.1764  -18.1706
            2   C8x C    18.1764  -16.7731
            3   C8x C    19.3643  -16.0744
            4   C8x C    20.5521  -16.7731
            5   C8y C    20.5521  -18.1706
            6   C8x C    19.3643  -18.9392
            7   O2a O    21.8098  -18.8693
            8   C1b C    22.9976  -18.1706
            9   C1c C    24.1855  -18.8693
            10  C1b C    25.4432  -18.1706
            11  O1a O    24.1855  -20.2667
            12  N1b N    26.6310  -18.8693
            13  C1b C    27.8188  -18.1706
            14  C1a C    16.9187  -18.9392
            15  C1b C    29.0765  -18.8693
            16  C8y C    30.2644  -18.1706
            17  C8x C    30.2644  -16.7731
            18  C8x C    31.4522  -16.0744
            19  C8y C    32.6400  -16.7731
            20  C8y C    32.6400  -18.1706
            21  C8x C    31.4522  -18.8693
            22  O2a O    33.8978  -16.0744
            23  C1a C    35.0856  -16.7731
            24  O2a O    33.8978  -18.8693
            25  C1a C    35.0856  -18.1706
            26  X   Cl   32.6306  -20.7598
BOND        26
            1     5   6 2
            2    12  13 1
            3     6   1 1
            4     1  14 1
            5    13  15 1
            6     5   7 1
            7    15  16 1
            8     7   8 1
            9     1   2 2
            10    8   9 1
            11    2   3 1
            12   16  17 2
            13   17  18 1
            14   18  19 2
            15   19  20 1
            16   20  21 2
            17   21  16 1
            18    9  10 1
            19   19  22 1
            20    3   4 2
            21   22  23 1
            22    9  11 1
            23   20  24 1
            24    4   5 1
            25   24  25 1
            26   10  12 1

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