KEGG   DRUG: D01369Help
Entry
D01369                      Drug                                   

Name
Bevantolol hydrochloride (JAN/USAN);
Calvan (TN);
Vantol (TN)
Formula
C20H27NO4. HCl
Exact mass
381.1707
Mol weight
381.8936
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-anginal;
Antihypertensive;
Cardiac depressant [anti-arrythmic]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
beta-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB06 Bevantolol
      D01369  Bevantolol hydrochloride (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D01369  Bevantolol hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Bevantolol
      D01369  Bevantolol hydrochloride (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
42864-78-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   O2a O    14.4598  -16.6293
            2   C1b C    15.6476  -15.9306
            3   C1c C    16.8355  -16.6293
            4   C1b C    18.0932  -15.9306
            5   O1a O    16.8355  -18.0267
            6   N1b N    19.2810  -16.6293
            7   C1b C    20.4688  -15.9306
            8   C1b C    21.7265  -16.6293
            9   C8y C    22.9144  -15.9306
            10  C8x C    22.9144  -14.5331
            11  C8x C    24.1022  -13.8344
            12  C8y C    25.2900  -14.5331
            13  C8y C    25.2900  -15.9306
            14  C8x C    24.1022  -16.6293
            15  O2a O    26.5478  -13.8344
            16  C1a C    27.7356  -14.5331
            17  O2a O    26.5478  -16.6293
            18  C1a C    27.7356  -15.9306
            19  C8y C    14.4598  -18.0293
            20  C8x C    13.2574  -18.7239
            21  C8y C    13.2578  -20.1239
            22  C8x C    14.4704  -20.8236
            23  C8x C    15.6728  -20.1290
            24  C8x C    15.6724  -18.7290
            25  C1a C    12.0401  -20.8276
            26  X   Cl   24.9306  -20.2698
BOND        26
            1     6   7 1
            2     7   8 1
            3     8   9 1
            4     1   2 1
            5     2   3 1
            6     9  10 2
            7    10  11 1
            8    11  12 2
            9    12  13 1
            10   13  14 2
            11   14   9 1
            12    3   4 1
            13   12  15 1
            14   15  16 1
            15    3   5 1
            16   13  17 1
            17   17  18 1
            18    4   6 1
            19    1  19 1
            20   19  20 2
            21   20  21 1
            22   21  22 2
            23   22  23 1
            24   23  24 2
            25   19  24 1
            26   21  25 1

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