KEGG   DRUG: D01383Help
Entry
D01383                      Drug                                   

Name
Pethidine hydrochloride (JP16);
Meperidine hydrochloride (USP);
Demerol (TN)
Product
  Generic
  Other
Formula
C15H21NO2. HCl
Exact mass
283.1339
Mol weight
283.7937
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Analgesic [narcotic]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
mu-opioid receptor agonist [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Antipsychotics
Opioid analgesics
Opioid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AB Phenylpiperidine derivatives
     N02AB02 Pethidine
      D01383  Pethidine hydrochloride (JP16); Meperidine hydrochloride (USP)
USP drug classification [BR:br08302]
 Analgesics
  Opioid Analgesics, Short-acting
   Meperidine
    D01383  Pethidine hydrochloride (JP16); Meperidine hydrochloride (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 8  Narcotics
  82  Non-alkaloidal narcotics
   821  Synthetic narcotics
    8211  Phenylpiperazines
     D01383  Pethidine hydrochloride (JP16); Meperidine hydrochloride (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    mu-opioid receptor
     Pethidine
      D01383  Meperidine hydrochloride (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01383  Pethidine hydrochloride
  D01383  Pethidine hydrochloride for injection
BRITE hierarchy
Other DBs
CAS: 
50-13-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   X   Cl   28.2452  -17.0804
            2   C8x C    21.1400  -14.4900
            3   C8y C    21.1400  -15.8900
            4   C8x C    22.3524  -16.5900
            5   C8x C    23.5649  -15.8900
            6   C8x C    23.5649  -14.4900
            7   C8x C    22.3524  -13.7900
            8   C1z C    19.9276  -16.5900
            9   C1x C    18.7321  -15.8996
            10  C1x C    17.5196  -16.5995
            11  N1y N    17.5194  -17.9995
            12  C1x C    18.7149  -18.6899
            13  C1x C    19.9274  -17.9900
            14  C1a C    16.2966  -18.7054
            15  C7a C    20.6276  -17.8024
            16  O7a O    22.0498  -17.8028
            17  O6a O    19.9429  -18.9883
            18  C1b C    22.7397  -18.9983
            19  C1a C    24.1497  -18.9988
BOND        19
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     3   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13    8  13 1
            14   11  14 1
            15    8  15 1
            16   15  16 1
            17   15  17 2
            18   16  18 1
            19   18  19 1

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