KEGG   DRUG: D01454Help
Entry
D01454                      Drug                                   

Name
Bupranolol hydrochloride (JP16)
Formula
C14H22ClNO2. HCl
Exact mass
307.1106
Mol weight
308.2439
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA19 Bupranolol
      D01454  Bupranolol hydrochloride (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Bupranolol
      D01454  Bupranolol hydrochloride (JP16)
    beta2-adrenergic receptor
     Bupranolol
      D01454  Bupranolol hydrochloride (JP16)
    beta3-adrenergic receptor
     Bupranolol
      D01454  Bupranolol hydrochloride (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01454  Bupranolol hydrochloride
BRITE hierarchy
Other DBs
CAS: 
15148-80-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   X   Cl   29.0500  -15.1900
            2   C8x C    17.7100  -15.4700
            3   C8y C    17.7100  -16.9400
            4   C8y C    16.4500  -14.7700
            5   O2a O    18.9700  -17.6400
            6   C8y C    16.4500  -17.6400
            7   C8x C    15.2600  -15.4700
            8   C1b C    20.1600  -16.9400
            9   C8x C    15.2600  -16.9400
            10  C1c C    21.4200  -17.6400
            11  C1b C    22.6800  -16.9400
            12  O1a O    21.4200  -19.0400
            13  N1b N    23.8700  -17.6400
            14  C1d C    25.1300  -16.9400
            15  X   Cl   16.4500  -19.0400
            16  C1a C    16.4500  -13.3700
            17  C1a C    26.3307  -17.6599
            18  C1a C    25.1531  -15.5402
            19  C1a C    26.3538  -16.2601
BOND        18
            1     2   3 1
            2     2   4 2
            3     3   5 1
            4     3   6 2
            5     4   7 1
            6     5   8 1
            7     6   9 1
            8     8  10 1
            9    10  11 1
            10   10  12 1
            11   11  13 1
            12   13  14 1
            13    7   9 2
            14    6  15 1
            15    4  16 1
            16   14  17 1
            17   14  18 1
            18   14  19 1

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