KEGG   DRUG: D01454Help
Entry
D01454                      Drug                                   

Name
Bupranolol hydrochloride (JP16)
Formula
C14H22ClNO2. HCl
Exact mass
307.1106
Mol weight
308.2439
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA19 Bupranolol
      D01454  Bupranolol hydrochloride (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Bupranolol
      D01454  Bupranolol hydrochloride (JP16)
    beta2-adrenergic receptor
     Bupranolol
      D01454  Bupranolol hydrochloride (JP16)
    beta3-adrenergic receptor
     Bupranolol
      D01454  Bupranolol hydrochloride (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01454  Bupranolol hydrochloride
BRITE hierarchy
Other DBs
CAS: 
15148-80-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   X   Cl   23.1661  -21.6550
            2   O2a O    15.5189  -17.5651
            3   C1b C    16.6944  -16.8737
            4   C1c C    17.9391  -17.5651
            5   C1b C    19.1837  -16.8737
            6   O1a O    17.9391  -18.9481
            7   N1b N    20.3592  -17.5651
            8   C1d C    21.6039  -16.8737
            9   C1a C    22.7900  -17.5848
            10  C1a C    21.6267  -15.4909
            11  C1a C    22.8128  -16.2020
            12  C8y C    15.5189  -18.9651
            13  C8y C    14.3203  -19.6573
            14  C8x C    14.3205  -21.0573
            15  C8x C    15.5330  -21.7572
            16  C8y C    16.7316  -21.0650
            17  C8x C    16.7314  -19.6650
            18  X   Cl   13.1356  -18.9734
            19  C1a C    17.9451  -21.7654
BOND        18
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     4   6 1
            5     5   7 1
            6     7   8 1
            7     8   9 1
            8     8  10 1
            9     8  11 1
            10    2  12 1
            11   12  13 2
            12   13  14 1
            13   14  15 2
            14   15  16 1
            15   16  17 2
            16   12  17 1
            17   13  18 1
            18   16  19 1

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