KEGG   DRUG: D01471Help
Entry
D01471                      Drug                                   

Name
Esatenolol (JAN/INN);
(S)-Atenolol
Formula
C14H22N2O3
Exact mass
266.163
Mol weight
266.3361
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Cardiovascular
Remark
ATC code: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB11 S-atenolol
      D01471  Esatenolol (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     S-atenolol
      D01471  Esatenolol (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
93379-54-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        19
            1   C8y C    24.1049  -18.3775
            2   C8x C    22.8991  -19.0882
            3   C8x C    24.0873  -16.9797
            4   O2a O    25.3280  -19.0532
            5   C8x C    21.6058  -18.4068
            6   C8x C    22.8641  -16.2865
            7   C1b C    26.5338  -18.3427
            8   C8y C    21.6643  -17.0030
            9   C1c C    27.7571  -19.0242
            10  C1b C    20.4526  -16.2981
            11  C1b C    28.9627  -18.3135
            12  O1a O    27.7745  -20.4222
            13  C5a C    19.2411  -17.0030
            14  N1b N    30.1744  -18.9951
            15  N1a N    18.0295  -16.2981
            16  O5a O    19.2411  -18.4068
            17  C1c C    31.3801  -18.2786
            18  C1a C    32.6033  -18.9602
            19  C1a C    31.3626  -16.8806
BOND        19
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     7   9 1
            9     8  10 1
            10    9  11 1
            11    9  12 1 #Down
            12   10  13 1
            13   11  14 1
            14   13  15 1
            15   13  16 2
            16   14  17 1
            17   17  18 1
            18   17  19 1
            19    6   8 2

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