KEGG   DRUG: D01473Help
Entry
D01473                      Drug                                   

Name
Flomoxef sodium (JP16);
FMOX;
S 6315;
Flumarin (TN)
Formula
C16H18F2N5O7S2. Na
Exact mass
517.0513
Mol weight
517.46
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibiotic;
Cephalosporin;
Cephalosporinase-resistant
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: broad spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DC Second-generation cephalosporins
     J01DC14 Flomoxef
      D01473  Flomoxef sodium (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6133  Oxacephem antibioitics
     D01473  Flomoxef sodium (JP16)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Oxacephems
     Flomoxef
      D01473  Flomoxef sodium (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01473  Flomoxef sodium
  D01473  Flomoxef sodium for injection
BRITE hierarchy
Other DBs
CAS: 
92823-03-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        33
            1   C1z C    28.5757  -14.7448
            2   C1y C    29.9570  -14.7448
            3   C5x C    28.5757  -16.1259
            4   N1y N    29.9453  -16.1202
            5   O2x O    31.1517  -14.0688
            6   C2y C    31.1400  -16.8136
            7   C1x C    32.3347  -14.7623
            8   C2y C    32.3288  -16.1319
            9   C6a C    31.1284  -18.1949
            10  C1b C    33.5177  -16.8312
            11  O6a O    29.9278  -18.8766
            12  O6a O    32.3171  -18.8883 #-
            13  S2a S    34.7239  -16.1493
            14  C8y C    35.9129  -16.8429
            15  N4y N    37.0089  -16.0034
            16  N5x N    36.3744  -18.1441
            17  N5x N    38.1499  -16.7923
            18  C1b C    37.0479  -14.6250
            19  N5x N    37.7528  -18.1132
            20  C1b C    38.2394  -13.9010
            21  C1b C    27.3633  -14.0448
            22  C5a C    26.1508  -14.7448
            23  O5a O    26.1508  -16.1259
            24  O5x O    27.3633  -16.8259
            25  C1b C    24.9711  -14.0639
            26  S2a S    23.7704  -14.7575
            27  C1c C    22.5855  -14.0736
            28  O2a O    28.5057  -13.3448
            29  C1a C    27.3628  -12.6443
            30  O1a O    39.4641  -14.5720
            31  X   F    21.3932  -14.7624
            32  X   F    22.5851  -12.6702
            33  Z   Na   33.8100  -18.9000 #+
BOND        34
            1     2   4 1
            2     2   5 1
            3     4   6 1
            4     5   7 1
            5     6   8 2
            6     6   9 1
            7     8  10 1
            8     9  11 2
            9     9  12 1
            10   10  13 1
            11   13  14 1
            12   14  15 1
            13   14  16 2
            14   15  17 1
            15   15  18 1
            16   16  19 1
            17    3   4 1
            18    7   8 1
            19   17  19 2
            20   18  20 1
            21    1   2 1
            22    1   3 1
            23    1  21 1 #Up
            24   21  22 1
            25   22  23 2
            26    3  24 2
            27   22  25 1
            28   25  26 1
            29   26  27 1
            30    1  28 1 #Down
            31   28  29 1
            32   20  30 1
            33   27  31 1
            34   27  32 1

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