KEGG   DRUG: D01491Help
Entry
D01491                      Drug                                   

Name
Butropium bromide (JP16/INN);
Coliopan (TN)
Formula
C28H38NO4. Br
Exact mass
531.1984
Mol weight
532.5096
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic
Remark
Therapeutic category: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiulcer drugs
Cholinergic and anticholinergic drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   124  Antispasmodics
    1242  Atropines
     D01491  Butropium bromide (JP16/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Butropium
      D01491  Butropium bromide (JP16/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01491  Butropium bromide
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D01491  Butropium bromide (JP15/INN)
BRITE hierarchy
Other DBs
CAS: 
29025-14-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        34
            1   C1x C    14.3738  -18.8808
            2   C1x C    14.7019  -17.7091
            3   C1y C    15.5455  -18.5996
            4   C1y C    15.8736  -17.4279
            5   N2y N    14.6082  -16.1156 #+
            6   C1x C    17.4202  -18.5996
            7   C1x C    17.1390  -17.4279
            8   C1y C    18.4513  -19.1620
            9   O7a O    19.5293  -20.0525
            10  C7a C    20.7479  -20.0525
            11  C1c C    21.3572  -18.9745
            12  O6a O    21.3572  -21.1773
            13  C8y C    22.5758  -18.9745
            14  C1b C    20.7479  -17.9434
            15  O1a O    21.3572  -16.8655
            16  C8x C    23.2820  -20.1982
            17  C8x C    24.6820  -20.1985
            18  C8x C    25.3822  -18.9862
            19  C8x C    24.6761  -17.7625
            20  C8x C    23.2761  -17.7622
            21  C1a C    13.8591  -14.9314
            22  C1b C    13.3789  -16.7283
            23  C8y C    12.2062  -15.9518
            24  C8x C    12.2062  -14.5518
            25  C8x C    10.9938  -13.8518
            26  C8y C     9.7813  -14.5518
            27  C8x C     9.7813  -15.9518
            28  C8x C    10.9938  -16.6518
            29  O2a O     8.5864  -13.8619
            30  C1b C     7.3926  -14.5513
            31  C1b C     6.2045  -13.8654
            32  C1b C     5.0136  -14.5531
            33  C1a C     3.8240  -13.8663
            34  X   Br   18.4100  -15.1200 #-
BOND        36
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1 #Down
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 1
            13   11  14 1 #Down
            14   14  15 1
            15    4   5 1
            16    7   8 1
            17   13  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   13  20 1
            23    5  21 1
            24    5  22 1
            25   22  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   23  28 1
            32   26  29 1
            33   29  30 1
            34   30  31 1
            35   31  32 1
            36   32  33 1

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