KEGG   DRUG: Butropium bromideHelp
Entry
D01491                      Drug                                   

Name
Butropium bromide (JP17/INN);
Coliopan (TN)
Formula
C28H38NO4. Br
Exact mass
531.1984
Mol weight
532.5096
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
Remark
Therapeutic category: 
Activity
Antispasmodic, Muscarinic acetylcholine receptor antagonist
Comment
Tropane derivative
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Salivary secretion
Gastric acid secretion
Interaction
Drug interaction
Structure map
Antiulcer drugs
Cholinergic and anticholinergic drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   124  Antispasmodics
    1242  Atropines
     D01491  Butropium bromide (JP17/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Butropium
      D01491  Butropium bromide (JP17/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01491  Butropium bromide
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D01491  Butropium bromide (JP15/INN)
Gastrointestinal agents [br08371.html]
 Antiulcer agent
  D01491
 Other gastrointestinal agents
  D01491
BRITE hierarchy
Other DBs
CAS: 
29025-14-7
PubChem: 
ChEBI: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        34
            1   C1x C    14.3738  -18.8808
            2   C1x C    14.7019  -17.7091
            3   C1y C    15.5455  -18.5996
            4   C1y C    15.8736  -17.4279
            5   N2y N    14.6082  -16.1156 #+
            6   C1x C    17.4202  -18.5996
            7   C1x C    17.1390  -17.4279
            8   C1y C    18.4513  -19.1620
            9   O7a O    19.5293  -20.0525
            10  C7a C    20.7479  -20.0525
            11  C1c C    21.3572  -18.9745
            12  O6a O    21.3572  -21.1773
            13  C8y C    22.5758  -18.9745
            14  C1b C    20.7479  -17.9434
            15  O1a O    21.3572  -16.8655
            16  C8x C    23.2820  -20.1982
            17  C8x C    24.6820  -20.1985
            18  C8x C    25.3822  -18.9862
            19  C8x C    24.6761  -17.7625
            20  C8x C    23.2761  -17.7622
            21  C1a C    13.8591  -14.9314
            22  C1b C    13.3789  -16.7283
            23  C8y C    12.2062  -15.9518
            24  C8x C    12.2062  -14.5518
            25  C8x C    10.9938  -13.8518
            26  C8y C     9.7813  -14.5518
            27  C8x C     9.7813  -15.9518
            28  C8x C    10.9938  -16.6518
            29  O2a O     8.5864  -13.8619
            30  C1b C     7.3926  -14.5513
            31  C1b C     6.2045  -13.8654
            32  C1b C     5.0136  -14.5531
            33  C1a C     3.8240  -13.8663
            34  X   Br   18.4100  -15.1200 #-
BOND        36
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1 #Down
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 1
            13   11  14 1 #Down
            14   14  15 1
            15    4   5 1
            16    7   8 1
            17   13  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   13  20 1
            23    5  21 1
            24    5  22 1
            25   22  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   23  28 1
            32   26  29 1
            33   29  30 1
            34   30  31 1
            35   31  32 1
            36   32  33 1

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