KEGG   DRUG: D01499Help
Entry
D01499                      Drug                                   

Name
Pivmecillinam hydrochloride (JP16);
Melysin (TN)
Formula
C21H33N3O5S. HCl
Exact mass
475.1908
Mol weight
476.0298
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Therapeutic category: 
ATC code: 
Comment
Semisynthetic penicillin: moderate spectrum penicillin
prodrug, active substance: Mecillinam [DR:D02888]
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Penicillins
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   612  Acting mainly on gram-negative bacteria
    6121  Penicillins
     D01499  Pivmecillinam hydrochloride (JP16)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA08 Pivmecillinam
      D01499  Pivmecillinam hydrochloride (JP16)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Penicillins
     Pivmecillinam [ATC:J01CA08]
      D01499  Pivmecillinam hydrochloride (JP16)
BRITE hierarchy
Other DBs
CAS: 
32887-03-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        31
            1   C1y C    12.9500  -20.9300
            2   C5x C    12.9500  -22.3300
            3   N1y N    14.3500  -22.3300
            4   C1y C    14.3500  -20.9300
            5   C1y C    15.6800  -22.7500
            6   C1z C    16.5200  -21.6300
            7   S2x S    15.6800  -20.5100
            8   C1a C    17.5000  -22.6100
            9   C1a C    17.5000  -20.6500
            10  C7a C    16.1700  -24.0800
            11  O7a O    17.5700  -24.0800
            12  O6a O    15.3300  -25.2700
            13  N2b N    11.7600  -20.2300
            14  C2b C    10.5700  -20.9300
            15  O5x O    11.7600  -23.0300
            16  N1y N     9.3100  -20.2300
            17  C1b C    18.2700  -25.3400
            18  O7a O    19.6700  -25.3400
            19  C7a C    20.3700  -24.1500
            20  O6a O    19.6700  -22.9600
            21  C1d C    21.7700  -24.1500
            22  C1a C    23.1700  -24.1500
            23  C1a C    21.7700  -22.7500
            24  C1a C    21.7700  -25.5500
            25  C1x C     9.3100  -18.8300
            26  C1x C     8.1900  -17.9200
            27  C1x C     6.8600  -18.2700
            28  C1x C     6.2300  -19.5300
            29  C1x C     6.8600  -20.7900
            30  C1x C     8.1900  -21.0700
            31  X   Cl   22.0500  -20.7900
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 2
            16    2  15 2
            17   14  16 1
            18   11  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 2
            22   19  21 1
            23   21  22 1
            24   21  23 1
            25   21  24 1
            26   27  28 1
            27   28  29 1
            28   26  27 1
            29   25  26 1
            30   29  30 1
            31   30  16 1
            32   25  16 1

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