KEGG   DRUG: D01504Help
Entry
D01504                      Drug                                   

Name
Bufetolol hydrochloride (JP16);
Adobiol (TN)
Formula
C18H29NO4. HCl
Exact mass
359.1863
Mol weight
359.8881
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   212  Antiarrhythmic agents
    2123  Beta blockers
     D01504  Bufetolol hydrochloride (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Bufetolol
      D01504  Bufetolol hydrochloride (JP16)
    beta2-adrenergic receptor
     Bufetolol
      D01504  Bufetolol hydrochloride (JP16)
    beta3-adrenergic receptor
     Bufetolol
      D01504  Bufetolol hydrochloride (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01504  Bufetolol hydrochloride
BRITE hierarchy
Other DBs
CAS: 
35108-88-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8y C    19.7695  -15.7602
            2   C8y C    19.7695  -14.3282
            3   C8x C    18.5430  -16.4704
            4   O2a O    21.0079  -13.6181
            5   C8x C    18.5430  -13.6181
            6   C8x C    17.3046  -15.7602
            7   C1b C    22.2462  -14.3282
            8   C8x C    17.3046  -14.3282
            9   C1c C    23.4728  -13.6241
            10  C1b C    24.7111  -14.3341
            11  O1a O    23.4728  -12.1978
            12  N1b N    25.9492  -13.6241
            13  C1d C    27.1758  -14.3341
            14  C1a C    28.3379  -14.8974
            15  C1a C    26.6829  -15.3963
            16  C1a C    27.7686  -13.0840
            17  O2a O    20.9859  -16.4613
            18  C1b C    22.2014  -15.7586
            19  C1y C    23.4180  -16.4598
            20  O2x O    23.4180  -17.8598
            21  C1x C    24.7495  -18.2924
            22  C1x C    25.5724  -17.1598
            23  C1x C    24.7495  -16.0272
            24  X   Cl   28.0767  -17.2793
BOND        24
            1     5   8 1
            2     7   9 1
            3     9  10 1
            4     9  11 1
            5    10  12 1
            6    12  13 1
            7    13  14 1
            8    13  15 1
            9    13  16 1
            10    6   8 2
            11    1  17 1
            12   17  18 1
            13    1   2 1
            14   18  19 1
            15    1   3 2
            16    2   4 1
            17    2   5 2
            18    3   6 1
            19    4   7 1
            20   19  20 1
            21   20  21 1
            22   21  22 1
            23   22  23 1
            24   19  23 1

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