KEGG   DRUG: D01543Help
Entry
D01543                      Drug                                   

Name
Nylidrin hydrochloride (JAN);
Buphenine hydrochloride;
Arlidin (TN)
Formula
C19H25NO2. HCl
Exact mass
335.1652
Mol weight
335.8682
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
ATC code: 
Drug group: 
Comment
Nylidrin is called Buphenine in INN.
Target
beta1-adrenergic receptor agonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor agonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C04 PERIPHERAL VASODILATORS
   C04A PERIPHERAL VASODILATORS
    C04AA 2-amino-1-phenylethanol derivatives
     C04AA02 Buphenine
      D01543  Nylidrin hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Buphenine
      D01543  Nylidrin hydrochloride (JAN)
    beta2-adrenergic receptor
     Buphenine
      D01543  Nylidrin hydrochloride (JAN)
    beta3-adrenergic receptor
     Buphenine
      D01543  Nylidrin hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
849-55-8
PubChem: 
LigandBox: 
KCF data Show

ATOM        23
            1   C8y C    36.8961  -16.7638
            2   C8x C    38.1073  -17.4650
            3   C8x C    39.3201  -16.7666
            4   C8x C    39.3218  -15.3671
            5   C8x C    38.1107  -14.6659
            6   C8x C    36.8978  -15.3642
            7   C8x C    25.9954  -17.4862
            8   C8y C    25.9954  -18.8886
            9   C8x C    27.2130  -19.5898
            10  C8x C    28.4233  -18.8886
            11  C8y C    28.4233  -17.4862
            12  C8x C    27.2130  -16.7850
            13  C1c C    29.6290  -16.7850
            14  C1c C    30.8402  -17.4791
            15  N1b N    32.0514  -16.7779
            16  C1c C    33.2626  -17.4721
            17  C1b C    34.4737  -16.7709
            18  C1b C    35.6849  -17.4650
            19  O1a O    24.7773  -19.5827
            20  O1a O    29.6221  -15.3826
            21  C1a C    30.8433  -18.8815
            22  C1a C    33.2656  -18.8745
            23  X   Cl   42.7700  -17.7100
BOND        23
            1    10  11 1
            2    11  12 2
            3    12   7 1
            4     5   6 2
            5    11  13 1
            6     6   1 1
            7    13  14 1
            8    14  15 1
            9    15  16 1
            10    1   2 2
            11   16  17 1
            12    2   3 1
            13   17  18 1
            14   18   1 1
            15    3   4 2
            16    8  19 1
            17    4   5 1
            18   13  20 1
            19    7   8 2
            20   14  21 1
            21    8   9 1
            22   16  22 1
            23    9  10 2

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