KEGG   DRUG: D01549Help
Entry
D01549                      Drug                                   

Name
Imidapril hydrochloride (JP16);
Tanatril (TN)
Formula
C20H27N3O6. HCl
Exact mass
441.1667
Mol weight
441.9058
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
prodrug, active substance: Imidaprilat
Target
angiotensin-converting enzyme (ACE) inhibitor [HSA:1636] [KO:K01283]
  Pathway
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Structure map
Renin-angiotensin system inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09A ACE INHIBITORS, PLAIN
    C09AA ACE inhibitors, plain
     C09AA16 Imidapril
      D01549  Imidapril hydrochloride (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2144  Angiotensin converting enzyme inhibitors
     D01549  Imidapril hydrochloride (JP16)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   angiotensin-converting enzyme (ACE)
    Imidapril
     D01549  Imidapril hydrochloride (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01549  Imidapril hydrochloride
  D01549  Imidapril hydrochloride tablets
BRITE hierarchy
Other DBs
CAS: 
89396-94-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   X   Cl   38.7644  -14.3286
            2   C8x C    21.8083  -15.6375
            3   C8x C    21.8083  -17.0398
            4   C8x C    23.0228  -17.7410
            5   C8x C    24.2373  -17.0398
            6   C8y C    24.2373  -15.6375
            7   C8x C    23.0228  -14.9363
            8   C1b C    25.4768  -14.9363
            9   C1b C    26.6914  -15.6375
            10  C1c C    27.9058  -14.9363
            11  N1b N    29.1202  -15.6375
            12  C1c C    30.3347  -14.9363
            13  C5a C    31.5491  -15.6375
            14  N1y N    32.7635  -14.9363
            15  C7a C    27.9058  -13.5340
            16  C1a C    30.3347  -13.5343
            17  O6a O    29.1223  -12.8316
            18  O7a O    26.6934  -12.8341
            19  C1b C    25.4969  -13.5250
            20  C1a C    24.3071  -12.8381
            21  O5a O    31.5491  -17.0398
            22  C5x C    33.8906  -15.7472
            23  N1y N    35.0069  -14.9244
            24  C1x C    34.5693  -13.6085
            25  C1y C    33.1826  -13.5481
            26  O5x O    33.8994  -17.1798
            27  C1a C    36.2214  -15.6256
            28  O6a O    33.1659  -11.1893
            29  C6a C    32.4732  -12.4085
            30  O6a O    31.0637  -12.4182
BOND        30
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     6   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13   13  14 1
            14   10  15 1 #Up
            15   12  16 1 #Up
            16   15  17 2
            17   15  18 1
            18   18  19 1
            19   19  20 1
            20   13  21 2
            21   14  22 1
            22   22  23 1
            23   23  24 1
            24   24  25 1
            25   14  25 1
            26   22  26 2
            27   23  27 1
            28   28  29 1
            29   25  29 1 #Down
            30   29  30 2

» Japanese version   » Back

DBGET integrated database retrieval system