KEGG   DRUG: D01550Help
Entry
D01550                      Drug                                   

Name
Liranaftate (JAN/INN);
Zefnart (TN)
Formula
C18H20N2O2S
Exact mass
328.1245
Mol weight
328.4286
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antifungal
Remark
Therapeutic category: 
Target
squalene epoxidase inhibitor [KO:K00511]
  Pathway
ko00100  Steroid biosynthesis  
 
Structure map
Antifungal agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   265  Antiparasitic dermatosis agents
    2659  Others
     D01550  Liranaftate (JAN/INN)
Antiinfectives [BR:br08307]
 Antifungals
  Ergosterol biosynthesis inhibitor
   squalene epoxidase inhibitor
    Thiocarbamates
     Liranaftate
      D01550  Liranaftate (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
88678-31-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C1x C    31.7323  -16.9596
            2   C8x C    20.8495  -17.6799
            3   C8y C    20.8495  -19.0759
            4   N5x N    22.0613  -19.7738
            5   C8y C    23.2661  -19.0759
            6   C8x C    23.2661  -17.6799
            7   C8x C    22.0613  -16.9819
            8   N1c N    24.4756  -19.7728
            9   C1a C    24.4766  -21.1688
            10  C2c C    25.6839  -19.0740
            11  O2a O    26.8934  -19.7711
            12  S0  S    25.6829  -17.6780
            13  C8y C    28.1019  -19.0721
            14  C8x C    29.3055  -19.7718
            15  C8x C    29.3035  -16.9799
            16  C8x C    28.0950  -17.6787
            17  C8y C    30.5079  -17.6723
            18  C8y C    30.5130  -19.0891
            19  C1x C    31.7423  -19.7931
            20  C1x C    32.9667  -19.0804
            21  C1x C    32.9618  -17.6636
            22  O2a O    19.6408  -19.7744
            23  C1a C    18.4315  -19.0769
BOND        25
            1    10  11 1
            2     4   5 2
            3    10  12 2
            4     5   6 1
            5    11  13 1
            6     6   7 2
            7     7   2 1
            8    13  14 2
            9    14  18 1
            10   17  15 1
            11   15  16 2
            12   16  13 1
            13    5   8 1
            14    8   9 1
            15    2   3 2
            16    8  10 1
            17   17  18 2
            18   18  19 1
            19   19  20 1
            20   20  21 1
            21   21   1 1
            22    1  17 1
            23    3   4 1
            24    3  22 1
            25   22  23 1

» Japanese version   » Back

DBGET integrated database retrieval system