KEGG   DRUG: Beraprost sodiumHelp
Entry
D01551                      Drug                                   

Name
Beraprost sodium (JP17/USAN);
Procylin (TN)
Formula
C24H29O5. Na
Exact mass
420.1913
Mol weight
420.4738
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01712  Antiplatelet agent
 DG01810  Prostacycline derivative
Unclassified
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
Remark
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Antihypertensive, Platelet aggregation inhibitor, Prostaglandin I2 receptor agonist
Comment
Prostacycline derivative
Target
prostaglandin I2 receptor [HSA:5739] [KO:K04263]
  Pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Interaction
Drug interaction
Structure map
Eicosanoids
Antithrombosis agents
Eicosanoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AC Platelet aggregation inhibitors excl. heparin
     B01AC19 Beraprost
      D01551  Beraprost sodium (JP17/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D01551  Beraprost sodium (JP17/USAN)
 3  Agents affecting metabolism
  33  Blood and body fluid agents
   339  Miscellaneous
    3399  Others
     D01551  Beraprost sodium (JP17/USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostacyclin
    prostaglandin I2 receptor
     Beraprost
      D01551  Beraprost sodium (JP17/USAN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01551  Beraprost sodium
  D01551  Beraprost sodium
Cardiovascular agents [br08364.html]
 Antihypertensives
  D01551
BRITE hierarchy
Other DBs
CAS: 
88475-69-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   C8y C    17.3439  -15.6088
            2   C8y C    18.0704  -16.8435
            3   C8x C    19.5032  -16.8315
            4   C8x C    20.2091  -15.5848
            5   C8x C    19.4824  -14.3501
            6   C8y C    18.0497  -14.3621
            7   C1y C    17.3730  -18.0855
            8   C1y C    16.0593  -17.6651
            9   C1y C    17.3672  -19.4753
            10  O2x O    16.0476  -16.2405
            11  C1x C    15.2534  -18.7922
            12  C1y C    16.0767  -19.9074
            13  C2b C    18.5700  -20.1585
            14  O1a O    15.6331  -21.2621
            15  C2b C    19.7612  -19.4753
            16  C1c C    20.9523  -20.1585
            17  C1c C    22.1436  -19.4753
            18  O1a O    20.9523  -21.5306
            19  C1b C    23.3347  -20.1585
            20  C3b C    24.5434  -19.4753
            21  C1a C    22.1436  -18.0782
            22  C1b C    17.3412  -13.1581
            23  C3b C    25.7470  -18.7697
            24  C1a C    26.9522  -18.0632
            25  C1b C    15.9723  -13.1698
            26  C1b C    15.2605  -11.9610
            27  C6a C    13.8713  -11.9730
            28  O6a O    13.1621  -10.7687 #-
            29  O6a O    13.1798  -13.1948
            30  Z   Na   10.3574  -10.7860 #+
BOND        31
            1     7   9 1
            2     7   2 1
            3     8  10 1
            4     8  11 1
            5     9  12 1
            6     9  13 1
            7    12  14 1
            8    13  15 2
            9    15  16 1
            10   16  17 1
            11   16  18 1
            12   17  19 1
            13   19  20 1
            14   10   1 1
            15   11  12 1
            16    5   6 2
            17   17  21 1
            18    6   1 1
            19    6  22 1
            20    1   2 2
            21    2   3 1
            22    3   4 2
            23    4   5 1
            24   20  23 3
            25    7   8 1
            26   23  24 1
            27   22  25 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   27  29 2

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