KEGG   DRUG: D01551Help
Entry
D01551                      Drug                                   

Name
Beraprost sodium (JP16/USAN);
Procylin (TN)
Formula
C24H29O5. Na
Exact mass
420.1913
Mol weight
420.4738
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Platelet aggregation inhibitor
Remark
Therapeutic category: 
ATC code: 
Comment
platelet aggregation inhibitor
Prostaglandin I2 derivative
Target
prostaglandin I2 receptor agonist [HSA:5739] [KO:K04263]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction  
 
Interaction
Drug interaction
Structure map
Eicosanoids
Antithrombosis agents
Eicosanoid receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D01551  Beraprost sodium (JP16/USAN)
 3  Agents affecting metabolism
  33  Blood and body fluid agents
   339  Miscellaneous
    3399  Others
     D01551  Beraprost sodium (JP16/USAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AC Platelet aggregation inhibitors excl. heparin
     B01AC19 Beraprost
      D01551  Beraprost sodium (JP16/USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostacyclin
    prostaglandin I2 receptor [HSA:5739] [KO:K04263]
     Beraprost [ATC:B01AC19]
      D01551  Beraprost sodium (JP16/USAN)
BRITE hierarchy
Other DBs
CAS: 
88475-69-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   C8y C    17.3439  -15.6088
            2   C8y C    18.0704  -16.8435
            3   C8x C    19.5032  -16.8315
            4   C8x C    20.2091  -15.5848
            5   C8x C    19.4824  -14.3501
            6   C8y C    18.0497  -14.3621
            7   C1y C    17.3730  -18.0855
            8   C1y C    16.0593  -17.6651
            9   C1y C    17.3672  -19.4753
            10  O2x O    16.0476  -16.2405
            11  C1x C    15.2534  -18.7922
            12  C1y C    16.0767  -19.9074
            13  C2b C    18.5700  -20.1585
            14  O1a O    15.6331  -21.2621
            15  C2b C    19.7612  -19.4753
            16  C1c C    20.9523  -20.1585
            17  C1c C    22.1436  -19.4753
            18  O1a O    20.9523  -21.5306
            19  C1b C    23.3347  -20.1585
            20  C3b C    24.5434  -19.4753
            21  C1a C    22.1436  -18.0782
            22  C1b C    17.3412  -13.1581
            23  C3b C    25.7470  -18.7697
            24  C1a C    26.9522  -18.0632
            25  C1b C    15.9723  -13.1698
            26  C1b C    15.2605  -11.9610
            27  C6a C    13.8713  -11.9730
            28  O6a O    13.1621  -10.7687 #-
            29  O6a O    13.1798  -13.1948
            30  Z   Na   10.3574  -10.7860 #+
BOND        31
            1     7   9 1
            2     7   2 1
            3     8  10 1
            4     8  11 1
            5     9  12 1
            6     9  13 1
            7    12  14 1
            8    13  15 2
            9    15  16 1
            10   16  17 1
            11   16  18 1
            12   17  19 1
            13   19  20 1
            14   10   1 1
            15   11  12 1
            16    5   6 2
            17   17  21 1
            18    6   1 1
            19    6  22 1
            20    1   2 2
            21    2   3 1
            22    3   4 2
            23    4   5 1
            24   20  23 3
            25    7   8 1
            26   23  24 1
            27   22  25 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   27  29 2

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