KEGG   DRUG: D01571Help
Entry
D01571                      Drug                                   

Name
Moxisylyte hydrochloride (JAN);
Opilon (TN)
Formula
C16H25NO3. HCl
Exact mass
315.1601
Mol weight
315.8355
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Vasodilator;
Peripheric;
alfa-Adrenergic blocking
Remark
ATC code: 
Drug group: 
Target
alpha1-adrenergic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C04 PERIPHERAL VASODILATORS
   C04A PERIPHERAL VASODILATORS
    C04AX Other peripheral vasodilators
     C04AX10 Moxisylyte
      D01571  Moxisylyte hydrochloride (JAN)
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G04 UROLOGICALS
   G04B UROLOGICALS
    G04BE Drugs used in erectile dysfunction
     G04BE06 Moxisylyte
      D01571  Moxisylyte hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Moxisylyte
      D01571  Moxisylyte hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
964-52-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C8y C    32.0672  -17.4899
            2   C8y C    30.8551  -18.1949
            3   C8x C    32.0672  -16.0912
            4   O2a O    33.2795  -18.1949
            5   C8x C    29.6371  -17.4899
            6   C1c C    30.8551  -19.5936
            7   C8y C    30.8551  -15.3918
            8   C1b C    34.4974  -17.4899
            9   C8y C    29.6428  -16.0971
            10  C1a C    30.8492  -13.9874
            11  C1b C    35.7097  -18.1949
            12  O7a O    28.4365  -15.3977
            13  N1c N    36.9277  -17.4899
            14  C7a C    27.2244  -16.0971
            15  C1a C    26.0063  -15.3977
            16  O6a O    27.2244  -17.4958
            17  C1a C    36.9262  -16.0955
            18  C1a C    38.1361  -18.1857
            19  C1a C    29.6477  -20.2908
            20  C1a C    32.0627  -20.2908
            21  X   Cl   42.3890  -17.8004
BOND        20
            1     2   5 1
            2     2   6 1
            3     3   7 2
            4     4   8 1
            5     5   9 2
            6     7  10 1
            7     8  11 1
            8     9  12 1
            9    11  13 1
            10   12  14 1
            11   14  15 1
            12   14  16 2
            13    7   9 1
            14   13  17 1
            15   13  18 1
            16    1   2 2
            17    6  19 1
            18    1   3 1
            19    6  20 1
            20    1   4 1

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