KEGG   DRUG: Etilefrine hydrochlorideHelp
Entry
D01573                      Drug                                   

Name
Etilefrine hydrochloride (JP17);
Etilefrine hydrochloride (TN)
Formula
C10H15NO2. HCl
Exact mass
217.087
Mol weight
217.6925
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01702  Phenethylamine cardiotonic
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01448  alpha1-Adrenergic receptor agonist
    DG01654  alpha1-Adrenergic receptor specific agonist
Remark
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Antihypotensive, Cardiotonic, Adrenergic receptor agonist
Comment
Phenethylamine derivative
Target
ADRA1 [HSA:148 147 146] [KO:K04135 K04136 K04137];
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140];
ADRB1 [HSA:153] [KO:K04141];
ADRB2 [HSA:154] [KO:K04142];
ADRB3 [HSA:155] [KO:K04143]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Salivary secretion
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA01 Etilefrine
      D01573  Etilefrine hydrochloride (JP17)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   211  Cardiotonics
    2119  Others
     D01573  Etilefrine hydrochloride (JP17)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Etilefrine
      D01573  Etilefrine hydrochloride (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01573  Etilefrine hydrochloride
  D01573  Etilefrine hydrochloride tablets
BRITE hierarchy
Other DBs
CAS: 
943-17-9
PubChem: 
ChEBI: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   C8y C    27.7200  -15.6100
            2   C8x C    27.7200  -17.0100
            3   C8x C    28.9100  -17.7100
            4   C8x C    30.1000  -17.0100
            5   C8y C    30.1000  -15.6100
            6   C8x C    28.9100  -14.9100
            7   C1c C    31.2900  -14.9100
            8   C1b C    32.5500  -15.6100
            9   N1b N    33.7400  -14.9100
            10  C1b C    34.9300  -15.6100
            11  C1a C    36.1900  -14.9100
            12  O1a O    31.2900  -13.5100
            13  O1a O    26.4600  -14.9100
            14  X   Cl   34.7900  -17.0800
BOND        13
            1     5   7 1
            2     7   8 1
            3     1   2 2
            4     8   9 1
            5     2   3 1
            6     9  10 1
            7     3   4 2
            8    10  11 1
            9     4   5 1
            10    7  12 1
            11    5   6 2
            12    1  13 1
            13    6   1 1

» Japanese version   » Back

DBGET integrated database retrieval system