KEGG   DRUG: D01573Help
Entry
D01573                      Drug                                   

Name
Etilefrine hydrochloride (JP16);
Etilefrine hydrochloride (TN)
Formula
C10H15NO2. HCl
Exact mass
217.087
Mol weight
217.6925
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypotensive;
Sympathomimetic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
alpha1-adrenergic receptor agonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA01 Etilefrine
      D01573  Etilefrine hydrochloride (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   211  Cardiotonics
    2119  Others
     D01573  Etilefrine hydrochloride (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Etilefrine
      D01573  Etilefrine hydrochloride (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01573  Etilefrine hydrochloride
  D01573  Etilefrine hydrochloride tablets
BRITE hierarchy
Other DBs
CAS: 
943-17-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   C8y C    27.7200  -15.6100
            2   C8x C    27.7200  -17.0100
            3   C8x C    28.9100  -17.7100
            4   C8x C    30.1000  -17.0100
            5   C8y C    30.1000  -15.6100
            6   C8x C    28.9100  -14.9100
            7   C1c C    31.2900  -14.9100
            8   C1b C    32.5500  -15.6100
            9   N1b N    33.7400  -14.9100
            10  C1b C    34.9300  -15.6100
            11  C1a C    36.1900  -14.9100
            12  O1a O    31.2900  -13.5100
            13  O1a O    26.4600  -14.9100
            14  X   Cl   34.7900  -17.0800
BOND        13
            1     5   7 1
            2     7   8 1
            3     1   2 2
            4     8   9 1
            5     2   3 1
            6     9  10 1
            7     3   4 2
            8    10  11 1
            9     4   5 1
            10    7  12 1
            11    5   6 2
            12    1  13 1
            13    6   1 1

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