KEGG   DRUG: D01592Help
Entry
D01592                      Drug                                   

Name
Betahistine mesilate (JP16);
Suzutolon (TN)
Formula
(CH4SO3)2. C8H12N2
Exact mass
328.0763
Mol weight
328.4056
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
H1-receptor agonist [HSA:3269] [KO:K04149];
H3-receptor antagonist [HSA:11255] [KO:K04151]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07C ANTIVERTIGO PREPARATIONS
    N07CA Antivertigo preparations
     N07CA01 Betahistine
      D01592  Betahistine mesilate (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   133  Vertigo agents
    1339  Others
     D01592  Betahistine mesilate (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Betahistine
      D01592  Betahistine mesilate (JP16)
    H3-receptor
     Betahistine
      D01592  Betahistine mesilate (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01592  Betahistine mesilate
  D01592  Betahistine mesilate tablets
BRITE hierarchy
Other DBs
CAS: 
54856-23-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   S4a S    31.4297  -18.3999
            2   O1d O    31.4368  -16.9981
            3   O1d O    31.4368  -19.8017
            4   C1a C    30.0279  -18.3999
            5   O1d O    32.8316  -18.3999
            6   C8x C    27.0676  -18.9723
            7   C8x C    27.0676  -17.5705
            8   N5x N    25.8507  -16.8695
            9   C8y C    24.6409  -17.5705
            10  C8x C    24.6409  -18.9723
            11  C8x C    25.8507  -19.6732
            12  C1b C    23.4356  -16.8764
            13  C1b C    22.2250  -17.5774
            14  N1b N    21.0143  -16.8836
            15  C1a C    19.8036  -17.5846
            16  S4a S    31.4297  -18.3999
            17  C1a C    30.0279  -18.3999
            18  O1d O    32.8316  -18.3999
            19  O1d O    31.4368  -16.9981
            20  O1d O    31.4368  -19.8017
BOND        18
            1     6   7 2
            2     7   8 1
            3     8   9 2
            4     9  10 1
            5    10  11 2
            6    11   6 1
            7     9  12 1
            8    12  13 1
            9    13  14 1
            10   14  15 1
            11    1   4 1
            12    1   5 1
            13    1   2 2
            14    1   3 2
            15   16  17 1
            16   16  18 1
            17   16  19 2
            18   16  20 2
BRACKET     1    28.3500  -20.0900   28.3500  -16.3800
            1    34.2300  -16.3800   34.2300  -20.0900
            1  2
 ORIGINAL  1    1   4   5   2   3
 REPEAT    1   16  17  18  19  20

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