KEGG   DRUG: D01596Help
Entry
D01596                      Drug                                   

Name
Oxytetracycline hydrochloride (JP16/USP);
OTC;
Terramycin (TN)
Formula
C22H24N2O9. HCl
Exact mass
496.1249
Mol weight
496.8949
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial;
Antirickettsial
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Tetracyclines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AA Tetracycline and derivatives
     D06AA03 Oxytetracycline
      D01596  Oxytetracycline hydrochloride (JP16/USP)
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AA Antibiotics
     G01AA07 Oxytetracycline
      D01596  Oxytetracycline hydrochloride (JP16/USP)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01A TETRACYCLINES
    J01AA Tetracyclines
     J01AA06 Oxytetracycline
      D01596  Oxytetracycline hydrochloride (JP16/USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA04 Oxytetracycline
      D01596  Oxytetracycline hydrochloride (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  27  Dental preparations
   276  Antibiotics
    2760  Antibiotics
     D01596  Oxytetracycline hydrochloride (JP16/USP)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for integumentary system
  56 Purulent skin remedies
   D01596  Oxytetracycline hydrochloride (JP16/USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Oxytetracycline
    D01596  Oxytetracycline hydrochloride (JP16/USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor
    Tetracyclines
     Oxytetracycline
      D01596  Oxytetracycline hydrochloride (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01596  Oxytetracycline hydrochloride
BRITE hierarchy
Other DBs
CAS: 
2058-46-0
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        34
            1   C1y C    26.2393  -17.1862
            2   C1z C    26.2160  -18.5600
            3   C1y C    25.0576  -16.4877
            4   C1y C    27.4383  -16.5110
            5   C2y C    25.0283  -19.2352
            6   C5x C    27.3976  -19.2644
            7   O1a O    26.2043  -19.9279
            8   C1y C    23.8527  -17.1629
            9   O1a O    25.0459  -14.8225
            10  C2y C    28.6141  -17.2154
            11  N1c N    27.4558  -15.1373
            12  C2y C    23.8410  -18.5367
            13  O1a O    25.0867  -20.6147
            14  C2y C    28.5965  -18.5949
            15  O5x O    27.3742  -20.6380
            16  C1z C    22.6652  -16.4643
            17  O1a O    29.8247  -16.5459
            18  C1a C    28.6606  -14.4621
            19  C1a C    27.4675  -13.4726
            20  C5x C    22.6535  -19.2235
            21  C5a C    29.7840  -19.2992
            22  C8y C    21.4662  -17.1512
            23  C1a C    22.6711  -14.6711
            24  C8y C    21.4603  -18.5309
            25  O5x O    22.6478  -20.6031
            26  N1a N    30.9831  -18.6298
            27  O5a O    29.7606  -20.6787
            28  C8x C    20.2729  -16.4643
            29  C8y C    20.2729  -19.2178
            30  C8x C    19.0797  -17.1512
            31  C8x C    19.0797  -18.5309
            32  O1a O    20.2787  -20.5972
            33  O1a O    21.4534  -15.7647
            34  X   Cl   33.7400  -16.5200
BOND        36
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     2   7 1 #Down
            7     3   8 1
            8     3   9 1 #Down
            9     4  10 1
            10    4  11 1 #Down
            11    5  12 2
            12    5  13 1
            13    6  14 1
            14    6  15 2
            15    8  16 1
            16   10  17 1
            17   11  18 1
            18   11  19 1
            19   12  20 1
            20   14  21 1
            21   16  22 1
            22   16  23 1 #Down
            23   20  24 1
            24   20  25 2
            25   21  26 1
            26   21  27 2
            27   22  28 2
            28   24  29 2
            29   28  30 1
            30   29  31 1
            31   29  32 1
            32    8  12 1
            33   10  14 2
            34   22  24 1
            35   30  31 2
            36   16  33 1 #Up

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