KEGG DRUG: D01618

DRUG: D01618

Entry

D01618 Drug

Name

Fradiomycin sulfate (JP16);
Neomycin sulfate (USP);
Mycifradin (TN);
Neo-fradin (TN);
Sofratulle (TN)

Product

Generic

NEOMYCIN SULFATE (Breckenridge Pharmaceutical), NEOMYCIN SULFATE (Golden State Medical Supply), NEOMYCIN SULFATE (HI TECH PHARMACAL), NEOMYCIN SULFATE (Major Pharmaceuticals), NEOMYCIN SULFATE (Teva Pharmaceuticals USA), NEOMYCIN SULFATE (X-GEN Pharmaceuticals), NEO-FRADIN (X-GEN Pharmaceuticals)

Activity

Antibacterial

Remark

Therapeutic category:

2634 2760

ATC code:

A01AB08 A07AA01 B05CA09 D06AX04 J01GB05 R02AB01 S01AA03 S02AA07 S03AA01

Target

16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]

Pathway

ko03010 Ribosome

Interaction

Structure map

map07021

Aminoglycosides

Brite

Therapeutic category of drugs in Japan [BR:br08301]
2  Agents affecting individual organs
  26  Epidermides
   263  Suppurative dermatosis agents
    2634  Antibiotics for external use
     D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
  27  Dental preparations
   276  Antibiotics
    2760  Antibiotics
     D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB08 Neomycin
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA01 Neomycin
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05C IRRIGATING SOLUTIONS
    B05CA Antiinfectives
     B05CA09 Neomycin
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX04 Neomycin
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB05 Neomycin
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
R RESPIRATORY SYSTEM
  R02 THROAT PREPARATIONS
   R02A THROAT PREPARATIONS
    R02AB Antibiotics
     R02AB01 Neomycin
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA03 Neomycin
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA07 Neomycin
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA01 Neomycin
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
USP drug classification [BR:br08302]
Antibacterials
  Aminoglycosides
   Neomycin
    D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)
Antiinfectives [BR:br08307]
Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor [KO:K01977]
    Aminoglycosides
     Neomycin [ATC:A01AB08 A07AA01 B05CA09 D06AX04 J01GB05 R02AB01 S01AA03 S02AA07 S03AA01]
      D01618  Fradiomycin sulfate (JP16); Neomycin sulfate (USP)

Other DBs

CAS:

1405-10-3

PubChem:

7848681

NIKKAJI:

J300.828B

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