KEGG   DRUG: D01627Help
Entry
D01627                      Drug                                   

Name
Diphenylpyraline teoclate (JAN);
Piprinhydrinate;
Plokon (TN)
Formula
C19H23NO. C7H7ClN4O2
Exact mass
495.2037
Mol weight
496.0011
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiperistaltic
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AA Aminoalkyl ethers
     R06AA07 Diphenylpyraline
      D01627  Diphenylpyraline teoclate (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Category 2
  Inorganic and organic chemicals
   Diphenylpyraline
    D01627  Diphenylpyraline teoclate (JAN)
 Category 3
  Inorganic and organic chemicals
   Diphenylpyraline
    D01627  Diphenylpyraline teoclate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Diphenylpyraline
      D01627  Diphenylpyraline teoclate (JAN)
BRITE hierarchy
Other DBs
CAS: 
606-90-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        35
            1   C8y C    26.6999  -16.4331
            2   C8y C    26.6999  -17.8571
            3   C8y C    27.8963  -15.7268
            4   N4x N    25.3926  -16.0011
            5   N4y N    27.8963  -18.5398
            6   N5x N    25.3926  -18.2888
            7   N4y N    29.1160  -16.4622
            8   O5x O    27.8963  -14.3495
            9   C8y C    24.5814  -17.1567
            10  C8y C    29.1160  -17.8045
            11  C1a C    27.8963  -19.9696
            12  C1a C    30.3649  -15.7852
            13  X   Cl   23.1807  -17.1625
            14  O5x O    30.3649  -18.5048
            15  C1c C    16.7797  -17.7374
            16  C8y C    15.5669  -18.4463
            17  C8y C    17.9982  -18.4463
            18  O2a O    16.7854  -16.3373
            19  C8x C    15.5669  -19.8406
            20  C8x C    14.3542  -17.7374
            21  C8x C    17.9924  -19.8406
            22  C1y C    17.9982  -15.6342
            23  C8x C    14.3542  -20.5379
            24  C8x C    13.1414  -18.4463
            25  C8x C    19.2052  -20.5379
            26  C8x C    20.4179  -18.4463
            27  C1x C    17.9982  -14.2339
            28  C8x C    13.1414  -19.8406
            29  C8x C    20.4120  -19.8406
            30  C1x C    19.2169  -13.5308
            31  N1y N    20.4237  -14.2339
            32  C8x C    19.2140  -17.7357
            33  C1a C    21.6404  -13.5378
            34  C1x C    20.4183  -15.6356
            35  C1x C    19.2016  -16.3317
BOND        38
            1     1   4 1
            2     2   5 1
            3     2   6 1
            4     3   7 1
            5     3   8 2
            6     4   9 1
            7     5  10 1
            8     5  11 1
            9     7  12 1
            10    9  13 1
            11   10  14 2
            12    6   9 2
            13    7  10 1
            14    1   2 2
            15    1   3 1
            16   15  16 1
            17   15  17 1
            18   15  18 1
            19   16  19 1
            20   16  20 2
            21   17  21 2
            22   17  32 1
            23   18  22 1
            24   19  23 2
            25   20  24 1
            26   21  25 1
            27   32  26 2
            28   22  27 1
            29   23  28 1
            30   25  29 2
            31   27  30 1
            32   30  31 1
            33   24  28 2
            34   26  29 1
            35   22  35 1
            36   31  33 1
            37   31  34 1
            38   34  35 1

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