KEGG   DRUG: D01667Help
Entry
D01667                      Drug                                   

Name
Delapril hydrochloride (JAN/USAN);
Adecut (TN)
Formula
C26H32N2O5. HCl
Exact mass
488.2078
Mol weight
489.0036
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive;
Enzyme inhibitor [angiotensin-converting]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
prodrug
Target
angiotensin-converting enzyme (ACE) inhibitor [HSA:1636] [KO:K01283]
  Pathway
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Structure map
Renin-angiotensin system inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09A ACE INHIBITORS, PLAIN
    C09AA ACE inhibitors, plain
     C09AA12 Delapril
      D01667  Delapril hydrochloride (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2144  Angiotensin converting enzyme inhibitors
     D01667  Delapril hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   angiotensin-converting enzyme (ACE)
    Delapril
     D01667  Delapril hydrochloride (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
83435-67-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        34
            1   X   Cl   37.4559  -15.8761
            2   N1c N    29.8858  -15.6358
            3   C1b C    29.8899  -14.2361
            4   N1b N    26.2614  -16.3406
            5   C1c C    25.0505  -15.6446
            6   C7a C    25.0445  -14.2407
            7   C1b C    23.8336  -16.3523
            8   O6a O    26.2614  -13.5387
            9   O7a O    23.8220  -13.5445
            10  C1b C    22.6171  -15.6621
            11  C8y C    21.4062  -16.3523
            12  C8x C    21.4062  -17.7680
            13  C8x C    20.2012  -15.6621
            14  C8x C    20.2012  -18.4757
            15  C8x C    18.9786  -16.3523
            16  C8x C    18.9786  -17.7680
            17  C1c C    27.4684  -15.6358
            18  C5a C    28.6771  -16.3355
            19  O5a O    28.6771  -17.7350
            20  C1a C    27.4657  -14.2363
            21  C6a C    31.1037  -13.5399
            22  O6a O    31.1078  -12.1403
            23  O6a O    32.3138  -14.2432
            24  C1y C    31.1192  -16.2173
            25  C8y C    33.3868  -16.2300
            26  C8y C    33.0052  -17.5552
            27  C8x C    33.8561  -18.6094
            28  C8x C    35.2298  -18.3384
            29  C8x C    35.6820  -17.0132
            30  C8x C    34.7605  -15.9591
            31  C1x C    31.6142  -17.5483
            32  C1x C    32.2662  -15.3947
            33  C1b C    22.6129  -14.2522
            34  C1a C    21.4062  -13.5652
BOND        35
            1    11  13 2
            2    12  14 2
            3    13  15 1
            4    14  16 1
            5    15  16 2
            6     4  17 1
            7    17  18 1
            8    18   2 1
            9    18  19 2
            10   17  20 1 #Up
            11    2   3 1
            12    3  21 1
            13   21  22 2
            14    4   5 1
            15   21  23 1
            16    5   6 1 #Up
            17    2  24 1
            18    5   7 1
            19    6   8 2
            20    6   9 1
            21    7  10 1
            22   10  11 1
            23   25  26 2
            24   26  27 1
            25   27  28 2
            26   28  29 1
            27   29  30 2
            28   30  25 1
            29   11  12 1
            30   24  31 1
            31   31  26 1
            32   25  32 1
            33   32  24 1
            34    9  33 1
            35   33  34 1

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