KEGG   DRUG: D01680Help
Entry
D01680                      Drug                                   

Name
Cefcapene pivoxil hydrochloride hydrate (JP16);
CFPN-PI;
S 1108;
Flomox (TN)
Formula
C23H29N5O8S2. HCl. H2O
Exact mass
621.133
Mol weight
622.1113
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibiotic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: broad spectrum cephalosporin
prodrug, active substance: Cefcapene [DR:D07638]
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Cephalosporins - oral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DD Third-generation cephalosporins
     J01DD17 Cefcapene
      D01680  Cefcapene pivoxil hydrochloride hydrate (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D01680  Cefcapene pivoxil hydrochloride hydrate (JP16)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefcapene
      D01680  Cefcapene pivoxil hydrochloride hydrate (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01680  Cefcapene pivoxil hydrochloride hydrate
  D01680  Cefcapene pivoxil hydrochloride fine granules
  D01680  Cefcapene pivoxil hydrochloride tablets
BRITE hierarchy
Other DBs
CAS: 
147816-24-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        40
            1   C1y C    25.7895  -18.0565
            2   N1y N    25.7895  -19.4438
            3   C2y C    26.9911  -20.1372
            4   C2y C    28.1924  -19.4438
            5   C1x C    28.1924  -18.0565
            6   S2x S    26.9911  -17.3629
            7   C1y C    24.4023  -18.0565
            8   C5x C    24.4023  -19.4438
            9   N1b N    23.2011  -17.3629
            10  C5a C    21.9995  -18.0565
            11  O5a O    21.9995  -19.4438
            12  O5x O    23.2011  -20.1372
            13  C2c C    20.7981  -17.3629
            14  C1b C    29.4122  -20.1483
            15  C8y C    19.5773  -18.0681
            16  O7a O    30.6186  -19.4521
            17  C7a C    31.8196  -20.1459
            18  C8x C    18.4326  -17.2621
            19  S2x S    17.3078  -18.1019
            20  C8y C    17.7588  -19.4311
            21  N5x N    19.1624  -19.4131
            22  N1a N    33.0574  -19.4314
            23  O6a O    31.8198  -21.5197
            24  C7a C    26.9910  -21.8681
            25  O7a O    25.7799  -22.5672
            26  O6a O    28.1900  -22.5602
            27  C1b C    24.5888  -21.8793
            28  O7a O    23.4100  -22.5596
            29  C7a C    22.2255  -21.8755
            30  C1d C    21.0435  -22.5577
            31  O6a O    22.2255  -20.4769
            32  C1a C    19.8385  -23.2535
            33  C1a C    20.3571  -21.3683
            34  C1a C    21.7480  -23.7785
            35  C2b C    20.7980  -15.9542
            36  N1a N    16.9265  -20.5677
            37  C1b C    22.0019  -15.2590
            38  C1a C    22.0019  -13.8590
            39  X   Cl   30.3226  -22.9812
            40  O0  O    33.3142  -22.9116
BOND        40
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16   13  15 1
            17   14  16 1
            18   16  17 1
            19   15  18 2
            20   18  19 1
            21   19  20 1
            22   20  21 2
            23   15  21 1
            24   17  22 1
            25   17  23 2
            26    3  24 1
            27   24  25 1
            28   24  26 2
            29   25  27 1
            30   27  28 1
            31   28  29 1
            32   29  30 1
            33   29  31 2
            34   30  32 1
            35   30  33 1
            36   30  34 1
            37   13  35 2
            38   20  36 1
            39   35  37 1
            40   37  38 1

» Japanese version   » Back

DBGET integrated database retrieval system