KEGG   DRUG: D01686Help
Entry
D01686                      Drug                                   

Name
Cefteram pivoxil (JP16);
CFTM-PI;
T 2588;
Tomiron (TN)
Formula
C22H27N9O7S2
Exact mass
593.1475
Mol weight
593.6359
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibiotic, cephalosporin
Remark
Therapeutic category: 
Drug group: 
Comment
Semisynthetic cephalosporin: broad spectrum cephalosporin
prodrug, active substance: Cefteram [DR:D07655]
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Cephalosporins - oral agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D01686  Cefteram pivoxil (JP16)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefteram
      D01686  Cefteram pivoxil (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01686  Cefteram pivoxil
  D01686  Cefteram pivoxil fine granules
  D01686  Cefteram pivoxil tablets
BRITE hierarchy
Other DBs
CAS: 
82547-81-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        40
            1   C1y C    25.4403  -17.6462
            2   N1y N    25.4403  -19.0212
            3   C2y C    26.6090  -19.7087
            4   C2y C    27.7778  -19.0212
            5   C1x C    27.7778  -17.6462
            6   S2x S    26.6090  -16.9587
            7   C1y C    24.0652  -17.6462
            8   C5x C    24.0652  -19.0212
            9   N1b N    22.8277  -16.9587
            10  C5a C    21.6590  -17.6462
            11  O5a O    21.6590  -19.0212
            12  O5x O    22.8277  -19.7087
            13  C2c C    20.4901  -16.9587
            14  C1b C    29.0153  -19.7087
            15  C8y C    19.2526  -17.6462
            16  N4y N    30.1842  -19.0212
            17  C8x C    18.2214  -16.8211
            18  S2x S    17.0526  -17.5774
            19  C8y C    17.4652  -18.9524
            20  N5x N    18.8401  -18.9524
            21  N2b N    20.4901  -15.5836
            22  C7a C    26.6090  -22.1835
            23  O7a O    27.7778  -22.8711
            24  O6a O    25.3715  -22.8711
            25  N1a N    16.6401  -20.0524
            26  N5x N    31.3135  -19.8099
            27  C8y C    32.4136  -18.9822
            28  N5x N    31.9664  -17.6801
            29  N5x N    30.5899  -17.7031
            30  C1a C    33.6042  -19.6695
            31  C1b C    28.9720  -22.1944
            32  O7a O    30.1291  -22.8752
            33  C7a C    31.3142  -22.2038
            34  C1d C    32.5138  -22.9099
            35  O6a O    31.3252  -20.8066
            36  C1a C    33.7045  -23.5973
            37  C1a C    31.8101  -24.1165
            38  C1a C    33.1952  -21.7417
            39  O2a O    21.7086  -14.8865
            40  C1a C    21.7086  -13.4865
BOND        43
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16   13  15 1
            17   14  16 1
            18   15  17 2
            19   17  18 1
            20   18  19 1
            21   19  20 2
            22   15  20 1
            23   13  21 2
            24    3  22 1
            25   22  23 1
            26   22  24 2
            27   19  25 1
            28   16  26 1
            29   26  27 2
            30   27  28 1
            31   28  29 2
            32   16  29 1
            33   27  30 1
            34   23  31 1
            35   31  32 1
            36   32  33 1
            37   33  34 1
            38   33  35 2
            39   34  36 1
            40   34  37 1
            41   34  38 1
            42   21  39 1
            43   39  40 1

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