| Entry |
|
|---|
| Name |
Mofezolac (JAN/INN);
Mofezolac (TN)
|
|---|
| Formula |
C19H17NO5
|
|---|
| Exact mass |
339.1107
|
|---|
| Mol weight |
339.342
|
|---|
| Structure |
     |
|---|
| Activity |
Anti-inflammatory
|
|---|
| Remark |
|
|---|
| Comment |
nonsteroidal antiinflammatory drugs (NSAIDs)
|
|---|
| Target |
cyclooxygenase-1 (COX-1) inhibitor [HSA: 5742] [KO: K00509] |
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
|
|---|
| Interaction |
|
|---|
| Structure map |
| 1,2-Diphenyl substitution family | | Cyclooxygenase inhibitors |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1149 Others
D01718 Mofezolac (JAN/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases
cyclooxygenase-1 (COX-1) [HSA:5742] [KO:K00509]
Mofezolac
D01718 Mofezolac (JAN/INN)
 |
|---|
| Other DBs |
CAS: 78967-07-4 PubChem: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 25
1 O2x O 28.2631 -17.3226
2 C8y C 27.4217 -16.2008
3 C8y C 26.1129 -16.6215
4 C8y C 26.1129 -18.0238
5 N5x N 27.4217 -18.4445
6 C8y C 22.4668 -14.5180
7 C8x C 22.4668 -15.9203
8 C8x C 23.6821 -16.6215
9 C8y C 24.8975 -15.9203
10 C8x C 24.8975 -14.5180
11 C8x C 23.6821 -13.8168
12 O2a O 21.2514 -13.8168
13 C1a C 20.0361 -14.5180
14 C8x C 22.4668 -18.7250
15 C8y C 22.4668 -20.1273
16 C8x C 23.6821 -20.8285
17 C8x C 24.8975 -20.1273
18 C8y C 24.8975 -18.7250
19 C8x C 23.6821 -18.0238
20 O2a O 21.2514 -20.8285
21 C1a C 20.0361 -20.1273
22 C1b C 27.8470 -14.8644
23 C6a C 29.2164 -14.5647
24 O6a O 30.1525 -15.5920
25 O6a O 29.6400 -13.2338
BOND 27
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 1 5 1
6 6 7 2
7 7 8 1
8 8 9 2
9 9 10 1
10 10 11 2
11 6 11 1
12 9 3 1
13 6 12 1
14 12 13 1
15 14 15 2
16 15 16 1
17 16 17 2
18 17 18 1
19 18 19 2
20 14 19 1
21 18 4 1
22 15 20 1
23 20 21 1
24 2 22 1
25 22 23 1
26 23 24 2
27 23 25 1
|
|---|
