KEGG   DRUG: D01753Help
Entry
D01753                      Drug                                   

Name
Dibekacin sulfate (JP16);
Panimycin (TN)
Formula
C18H37N5O8. xH2SO4
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibiotic, aminoglycoside
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB09 Dibekacin
      D01753  Dibekacin sulfate (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1317  Ophthalmic antibiotics
     D01753  Dibekacin sulfate (JP16)
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6134  Amino sugars
     D01753  Dibekacin sulfate (JP16)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor
    Aminoglycosides
     Dibekacin
      D01753  Dibekacin sulfate (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01753  Dibekacin sulfate
  D01753  Dibekacin sulfate ophthalmic solution
BRITE hierarchy
Other DBs
CAS: 
58580-55-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        36
            1   O1d O    29.9635  -18.6462
            2   S4a S    31.3576  -18.6462
            3   O1d O    31.3506  -20.0402
            4   O1d O    32.7516  -18.6462
            5   O1d O    31.3506  -17.2522
            6   C1y C    19.7925  -17.1321
            7   C1y C    19.7925  -18.5332
            8   C1y C    21.0098  -19.2370
            9   C1y C    22.2198  -18.5332
            10  C1y C    22.2198  -17.1321
            11  O2x O    21.0098  -16.4351
            12  N1a N    21.0115  -20.6382
            13  O1a O    18.5786  -19.2377
            14  O1a O    23.4347  -19.2362
            15  O2a O    23.4347  -16.4359
            16  C1y C    24.6364  -15.7241
            17  C1y C    25.8547  -16.4192
            18  C1x C    26.9935  -15.7073
            19  C1y C    27.0539  -14.3071
            20  C1y C    25.8354  -13.6189
            21  C1y C    24.6268  -14.3238
            22  N1a N    25.8643  -17.8203
            23  N1a N    28.2631  -13.6018
            24  O2a O    25.8258  -12.2179
            25  O1a O    23.4146  -13.6353
            26  C1y C    27.0353  -11.5054
            27  O2x O    28.2460  -12.2029
            28  C1y C    29.4554  -11.4905
            29  C1x C    29.4457  -10.0894
            30  C1x C    28.2266   -9.4008
            31  C1y C    27.0174  -10.1061
            32  C1b C    30.6745  -12.1862
            33  N1a N    30.6841  -13.5871
            34  N1a N    25.7962   -9.4211
            35  C1b C    18.5786  -16.4344
            36  O1a O    17.3639  -17.1309
BOND        37
            1     2   5 2
            2     1   2 1
            3     2   3 2
            4     2   4 1
            5     6   7 1
            6     7   8 1
            7     8   9 1
            8    16  17 1
            9    17  18 1
            10   18  19 1
            11   19  20 1
            12   20  21 1
            13   21  16 1
            14    9  10 1
            15   17  22 1 #Up
            16   10  11 1
            17   19  23 1 #Up
            18   11   6 1
            19   20  24 1 #Down
            20   21  25 1 #Up
            21    8  12 1 #Up
            22   26  24 1 #Down
            23    7  13 1 #Down
            24    9  14 1 #Down
            25   26  27 1
            26   27  28 1
            27   28  29 1
            28   29  30 1
            29   30  31 1
            30   31  26 1
            31   10  15 1 #Down
            32   28  32 1 #Up
            33   32  33 1
            34   16  15 1 #Down
            35   31  34 1 #Down
            36    6  35 1 #Up
            37   35  36 1
BRACKET     1    28.4900  -20.9300   28.4900  -16.3100
            1    33.9500  -16.3100   33.9500  -20.9300
            1  x
 ORIGINAL  1    1   2   3   4   5
 REPEAT    1

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