KEGG   DRUG: D01773Help
Entry
D01773                      Drug                                   

Name
Oxatomide (JAN/USAN/INN);
Celtect (TN)
Formula
C27H30N4O
Exact mass
426.242
Mol weight
426.5533
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-asthmatic;
Anti-allergic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149];
arachidonate 5-lipoxygenase inhibitor [HSA:240] [KO:K00461]
  Pathway
hsa00590  Arachidonic acid metabolism
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AE Piperazine derivatives
     R06AE06 Oxatomide
      D01773  Oxatomide (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  44  Allergic agents
   449  Miscellaneous
    4490  Miscellaneous
     D01773  Oxatomide (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Oxatomide
      D01773  Oxatomide (JAN/USAN/INN)
 Enzymes
  Oxidoreductases
   arachidonate 5-lipoxygenase
    Oxatomide
     D01773  Oxatomide (JAN/USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
60607-34-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        32
            1   C8x C    27.0044  -21.8136
            2   C8x C    27.0044  -23.2147
            3   C8x C    28.2206  -23.9152
            4   C8x C    29.4298  -23.2147
            5   C8y C    29.4298  -21.8136
            6   C8x C    28.2206  -21.1131
            7   C1c C    30.6435  -21.1140
            8   C8y C    31.8564  -21.8153
            9   N1y N    30.6447  -19.7129
            10  C8x C    31.8497  -23.2145
            11  C8x C    33.0626  -23.9159
            12  C8x C    34.2765  -23.2162
            13  C8x C    34.2775  -21.8152
            14  C8x C    33.0647  -21.1138
            15  C1x C    31.8594  -19.0170
            16  C1x C    31.8604  -17.6160
            17  N1y N    30.6476  -16.9144
            18  C1x C    29.4338  -17.6141
            19  C1x C    29.4328  -19.0151
            20  C1b C    30.6488  -15.5134
            21  C1b C    31.8625  -14.8139
            22  C1b C    33.0761  -15.5158
            23  N4y N    34.3034  -14.8080
            24  C8y C    34.3034  -13.4080
            25  C8y C    35.6349  -15.2406
            26  C8y C    36.4578  -14.1080
            27  N4x N    35.6349  -12.9754
            28  O5x O    33.1838  -12.5950
            29  C8x C    37.8696  -14.1077
            30  C8x C    38.5842  -15.3441
            31  C8x C    37.8873  -16.5523
            32  C8x C    36.4704  -16.5533
BOND        36
            1     7   8 1
            2     2   3 1
            3     7   9 1
            4     9  15 1
            5    15  16 1
            6    16  17 1
            7    17  18 1
            8    18  19 1
            9    19   9 1
            10    3   4 2
            11   17  20 1
            12    4   5 1
            13   20  21 1
            14    5   6 2
            15    6   1 1
            16    8  10 2
            17   10  11 1
            18   11  12 2
            19   12  13 1
            20   13  14 2
            21   14   8 1
            22    5   7 1
            23    1   2 2
            24   21  22 1
            25   22  23 1
            26   23  24 1
            27   23  25 1
            28   25  26 2
            29   26  27 1
            30   24  27 1
            31   24  28 2
            32   26  29 1
            33   29  30 2
            34   30  31 1
            35   31  32 2
            36   32  25 1

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