KEGG   DRUG: D01806Help
Entry
D01806                      Drug                                   

Name
Oxprenolol hydrochloride (JP16/USP);
Okuspurecol (TN)
Formula
C15H23NO3. HCl
Exact mass
301.1445
Mol weight
301.809
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Vasodilator [coronary]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA02 Oxprenolol
      D01806  Oxprenolol hydrochloride (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   212  Antiarrhythmic agents
    2123  Beta blockers
     D01806  Oxprenolol hydrochloride (JP16/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Oxprenolol
      D01806  Oxprenolol hydrochloride (JP16/USP)
    beta2-adrenergic receptor
     Oxprenolol
      D01806  Oxprenolol hydrochloride (JP16/USP)
    beta3-adrenergic receptor
     Oxprenolol
      D01806  Oxprenolol hydrochloride (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01806  Oxprenolol hydrochloride
BRITE hierarchy
Other DBs
CAS: 
6452-73-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   C8x C    15.2600  -14.7700
            2   C8x C    15.2600  -13.3700
            3   C8x C    16.5200  -12.6700
            4   C8x C    17.7100  -13.3700
            5   C8y C    17.7100  -14.7700
            6   C8y C    16.5200  -15.4700
            7   O2a O    18.9000  -15.4700
            8   C1b C    20.0900  -14.7700
            9   C1c C    21.3500  -15.4700
            10  C1b C    22.5400  -14.7700
            11  N1b N    23.7300  -15.4700
            12  C1c C    24.9900  -14.7700
            13  C1a C    26.1800  -15.4700
            14  O1a O    21.3500  -16.8700
            15  C1a C    24.9900  -13.3700
            16  O2a O    16.5200  -16.8700
            17  C1b C    17.7100  -17.5700
            18  C2b C    17.7100  -18.9700
            19  C2a C    18.9000  -19.6700
            20  X   Cl   28.9800  -18.0600
BOND        19
            1     2   3 1
            2     9  10 1
            3     3   4 2
            4    10  11 1
            5     4   5 1
            6    11  12 1
            7     5   6 2
            8    12  13 1
            9     6   1 1
            10    9  14 1
            11   12  15 1
            12    5   7 1
            13    6  16 1
            14   16  17 1
            15    7   8 1
            16   17  18 1
            17    1   2 2
            18   18  19 2
            19    8   9 1

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