KEGG   DRUG: D01815Help
Entry
D01815                      Drug                                   

Name
Oxapium iodide (JP16/INN);
Espalexan (TN)
Formula
C22H34NO2. I
Exact mass
471.1634
Mol weight
471.4153
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic
Remark
Therapeutic category: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiulcer drugs
Cholinergic and anticholinergic drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   123  Autonomic nervous system agents
    1231  Quaternary ammoniums
     D01815  Oxapium iodide (JP16/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Oxapium
      D01815  Oxapium iodide (JP16/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01815  Oxapium iodide
BRITE hierarchy
Other DBs
CAS: 
6577-41-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   X   I    16.3999  -21.9516 #-
            2   O2x O    19.2720  -18.5831
            3   C1y C    18.1379  -19.4076
            4   C1x C    18.5716  -20.7410
            5   O2x O    19.9737  -20.7406
            6   C1z C    20.4066  -19.4070
            7   C1y C    20.4066  -18.0049
            8   C8y C    21.6208  -20.1080
            9   C1b C    16.9361  -18.7233
            10  N2y N    15.7218  -19.4244 #+
            11  C1x C    14.5075  -18.7233
            12  C1x C    13.2933  -19.4244
            13  C1x C    13.2933  -20.8265
            14  C1x C    14.5075  -21.5276
            15  C1x C    15.7218  -20.8265
            16  C1a C    15.7218  -18.0223
            17  C1x C    21.6036  -17.3138
            18  C1x C    21.6038  -15.9117
            19  C1x C    20.3896  -15.2106
            20  C1x C    19.1925  -15.9016
            21  C1x C    19.1924  -17.3037
            22  C8x C    21.6208  -21.5101
            23  C8x C    22.8351  -22.2112
            24  C8x C    24.0494  -21.5101
            25  C8x C    24.0494  -20.1080
            26  C8x C    22.8351  -19.4070
BOND        28
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     2   6 1
            6     6   7 1
            7     6   8 1
            8     3   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13   13  14 1
            14   14  15 1
            15   15  10 1
            16   10  16 1
            17    7  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22    7  21 1
            23    8  22 2
            24   22  23 1
            25   23  24 2
            26   24  25 1
            27   25  26 2
            28    8  26 1

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