KEGG   DRUG: D01840Help
Entry
D01840                      Drug                                   

Name
Fasudil hydrochloride (JAN)
Formula
C14H17N3O2S. HCl
Exact mass
327.0808
Mol weight
327.8296
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
ATC code: 
Drug group: 
Target
Rho-associated protein kinase (ROCK) inhibitor [HSA:6093 9475] [KO:K04514 K17388]
  Pathway
hsa04810  Regulation of actin cytoskeleton  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C04 PERIPHERAL VASODILATORS
   C04A PERIPHERAL VASODILATORS
    C04AX Other peripheral vasodilators
     C04AX32 Fasudil
      D01840  Fasudil hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Serine/threonine protein kinases: AGC group
   DMPK family
    rho-associated protein kinase (ROCK)
     Fasudil
      D01840  Fasudil hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
105628-07-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   X   Cl   36.4277  -15.8330
            2   C1x C    30.6534  -14.4994
            3   C1x C    29.8113  -13.3898
            4   C1x C    30.1465  -12.0330
            5   N1x N    31.4075  -11.4549
            6   N1y N    32.0592  -14.5246
            7   C1x C    32.6611  -12.0772
            8   C1x C    32.9476  -13.4459
            9   S4a S    32.0592  -15.9246
            10  C8y C    32.0592  -17.3246
            11  O3c O    33.4596  -15.9246
            12  O3c O    30.6604  -15.9246
            13  C8x C    30.8624  -18.0151
            14  C8x C    30.8620  -19.4151
            15  C8x C    32.0743  -20.1155
            16  C8y C    33.2711  -19.4249
            17  C8y C    33.2715  -18.0249
            18  C8x C    34.4833  -20.1253
            19  N5x N    35.6959  -19.4256
            20  C8x C    35.6963  -18.0256
            21  C8x C    34.4841  -17.3253
BOND        22
            1     4   5 1
            2     2   6 1
            3     5   7 1
            4     3   4 1
            5     6   8 1
            6     2   3 1
            7     7   8 1
            8     6   9 1
            9     9  10 1
            10    9  11 2
            11    9  12 2
            12   10  13 2
            13   13  14 1
            14   14  15 2
            15   15  16 1
            16   16  17 2
            17   10  17 1
            18   16  18 1
            19   18  19 2
            20   19  20 1
            21   20  21 2
            22   17  21 1

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