| Entry |
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| Name |
Pitavastatin calcium (JAN);
NK 104;
Livalo (TN)
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| Product |
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| Formula |
(C25H23FNO4)2. Ca
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| Exact mass |
880.2848
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| Mol weight |
880.9836
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| Structure |
     |
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| Activity |
Antihyperlipidemic
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| Remark |
Therapeutic category: ATC code: |
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| Target |
hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor [HSA: 3156] [KO: K00021] |
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| Pathway |
hsa00900 Terpenoid backbone biosynthesis | |
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| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
Transporter: SLCO1B1 [HSA: 10599], SLCO1B3 [HSA: 28234]
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| Interaction |
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| Pathway map |
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| Structure map |
| HMG-CoA reductase inhibitors |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
218 Hyperlipidemia agents
2189 Others
D01862 Pitavastatin calcium (JAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C10 LIPID MODIFYING AGENTS
C10A LIPID MODIFYING AGENTS, PLAIN
C10AA HMG CoA reductase inhibitors
C10AA08 Pitavastatin
D01862 Pitavastatin calcium (JAN)
USP drug classification [BR:br08302]
Cardiovascular Agents
Dyslipidemics, HMG CoA Reductase Inhibitors
Pitavastatin
D01862 Pitavastatin calcium (JAN)
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases
hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase [HSA:3156] [KO:K00021]
Pitavastatin [ATC:C10AA08]
D01862 Pitavastatin calcium (JAN)
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| Other DBs |
CAS: 147526-32-7 PubChem: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 63
1 Z Ca 38.8500 -13.7900 #2+
2 C8x C 22.4000 -15.1200
3 C8x C 22.4000 -16.5200
4 C8x C 23.5900 -17.2200
5 C8y C 24.8500 -16.5200
6 C8y C 24.8500 -15.1200
7 C8x C 23.5900 -14.4200
8 N5x N 26.0400 -17.2200
9 C8y C 27.2300 -16.5200
10 C8y C 27.2300 -15.1200
11 C8y C 26.0400 -14.4200
12 C8y C 26.0400 -13.0200
13 C8x C 27.2300 -12.3200
14 C8x C 27.2300 -10.9200
15 C8y C 26.0400 -10.2200
16 C8x C 24.8500 -10.9200
17 C8x C 24.8500 -12.3200
18 C2b C 28.4200 -14.4200
19 C2b C 29.6100 -15.1200
20 X F 26.0400 -8.8200
21 C1y C 28.4200 -17.2200
22 C1c C 30.8000 -14.4200
23 C1b C 31.9900 -15.1200
24 C1c C 33.1800 -14.4200
25 C1b C 34.3700 -15.1200
26 O1a O 30.8000 -13.0200
27 O1a O 33.1800 -13.0200
28 C6a C 35.5600 -14.4200
29 O6a O 36.7500 -15.1200 #-
30 O6a O 35.5600 -13.0200
31 C1x C 29.8200 -17.2200
32 C1x C 29.1200 -18.4100
33 C8x C 22.4000 -15.1200
34 C8x C 22.4000 -16.5200
35 C8x C 23.5900 -17.2200
36 C8y C 24.8500 -16.5200
37 C8y C 24.8500 -15.1200
38 C8x C 23.5900 -14.4200
39 C8y C 26.0400 -14.4200
40 C8y C 27.2300 -15.1200
41 C8y C 27.2300 -16.5200
42 N5x N 26.0400 -17.2200
43 C1y C 28.4200 -17.2200
44 C1x C 29.1200 -18.4100
45 C1x C 29.8200 -17.2200
46 C2b C 28.4200 -14.4200
47 C2b C 29.6100 -15.1200
48 C1c C 30.8000 -14.4200
49 C1b C 31.9900 -15.1200
50 C1c C 33.1800 -14.4200
51 C1b C 34.3700 -15.1200
52 C6a C 35.5600 -14.4200
53 O6a O 36.7500 -15.1200 #-
54 O6a O 35.5600 -13.0200
55 O1a O 33.1800 -13.0200
56 O1a O 30.8000 -13.0200
57 C8y C 26.0400 -13.0200
58 C8x C 27.2300 -12.3200
59 C8x C 27.2300 -10.9200
60 C8y C 26.0400 -10.2200
61 C8x C 24.8500 -10.9200
62 C8x C 24.8500 -12.3200
63 X F 26.0400 -8.8200
BOND 68
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 5 8 1
8 8 9 2
9 9 10 1
10 10 11 2
11 6 11 1
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 15 16 1
17 16 17 2
18 12 17 1
19 10 18 1
20 18 19 2
21 15 20 1
22 9 21 1
23 19 22 1
24 22 23 1
25 23 24 1
26 24 25 1
27 22 26 1 #Up
28 24 27 1 #Up
29 25 28 1
30 28 29 1
31 28 30 2
32 32 31 1
33 32 21 1
34 21 31 1
35 33 34 2
36 34 35 1
37 35 36 2
38 36 37 1
39 37 38 2
40 33 38 1
41 36 42 1
42 42 41 2
43 41 40 1
44 40 39 2
45 37 39 1
46 39 57 1
47 57 58 2
48 58 59 1
49 59 60 2
50 60 61 1
51 61 62 2
52 57 62 1
53 40 46 1
54 46 47 2
55 60 63 1
56 41 43 1
57 47 48 1
58 48 49 1
59 49 50 1
60 50 51 1
61 48 56 1 #Up
62 50 55 1 #Up
63 51 52 1
64 52 53 1
65 52 54 2
66 44 45 1
67 44 43 1
68 43 45 1
BRACKET 1 22.0500 -18.8300 22.0500 -8.4000
1 37.4500 -8.4000 37.4500 -18.8300
1 2
ORIGINAL 1 2 3 4 5 6 7 11 10 9 8 21 32 31 18 19 22
1 23 24 25 28 29 30 27 26 12 13 14 15 16 17 20
REPEAT 1 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48
1 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63
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