KEGG   DRUG: D01877Help
Entry
D01877                      Drug                                   

Name
Mefruside (JP16/USAN/INN);
Baycaron (TN)
Formula
C13H19ClN2O5S2
Exact mass
382.0424
Mol weight
382.8834
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Diuretic
Remark
Therapeutic category: 
ATC code: 
Target
Na+-Cl- symport inhibitor [HSA:6559] [KO:K14426]
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Ion transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C03 DIURETICS
   C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES
    C03BA Sulfonamides, plain
     C03BA05 Mefruside
      D01877  Mefruside (JP16/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   213  Diuretics
    2135  Chlorbenzene sulfonamides
     D01877  Mefruside (JP16/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A3
     Mefruside
      D01877  Mefruside (JP16/USAN/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01877  Mefruside
  D01877  Mefruside tablets
BRITE hierarchy
Other DBs
CAS: 
7195-27-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C8y C    24.5817  -18.9007
            2   S4a S    25.7900  -18.1993
            3   N1c N    26.9988  -18.8993
            4   O3c O    24.5887  -17.4923
            5   O3c O    27.0061  -17.4992
            6   C1b C    28.2068  -18.1981
            7   C1a C    26.9994  -20.2937
            8   C1z C    29.4087  -18.8981
            9   C1x C    30.6793  -18.3197
            10  C1x C    31.6153  -19.3572
            11  C1x C    30.9151  -20.5660
            12  O2x O    29.4110  -20.2782
            13  C1a C    29.4164  -17.4992
            14  C8x C    23.3813  -18.2280
            15  C8x C    24.5933  -20.2751
            16  C8y C    22.1983  -18.9298
            17  C8x C    23.4102  -20.9882
            18  C8y C    22.2042  -20.3099
            19  S4a S    20.9863  -18.2571
            20  X   Cl   21.0211  -21.0230
            21  N1a N    21.8155  -17.1264
            22  O3c O    20.0645  -19.5501
            23  O3c O    19.7339  -17.5729
BOND        24
            1    11  12 1
            2    12   8 1
            3     1   2 1
            4     8  13 1
            5     3   7 1
            6     2   4 2
            7     6   8 1
            8     2   5 2
            9     2   3 1
            10    3   6 1
            11    8   9 1
            12    9  10 1
            13   10  11 1
            14    1  14 1
            15    1  15 2
            16   14  16 2
            17   15  17 1
            18   16  18 1
            19   16  19 1
            20   18  20 1
            21   19  21 1
            22   19  22 2
            23   19  23 2
            24   17  18 2

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