KEGG   DRUG: D01888Help
Entry
D01888                      Drug                                   

Name
Safrazine hydrochloride (JAN)
Formula
C11H16N2O2. HCl
Exact mass
244.0979
Mol weight
244.7179
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Remark
Drug group: 
Comment
withdrawal drug
Target
monoamine oxidase (MAO) inhibitor [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Structure map
Catecholamine transferase inhibitors
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase (MAO)
    Safrazine
     D01888  Safrazine hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
7296-30-2
PubChem: 
LigandBox: 
KCF data Show

ATOM        16
            1   C8y C    20.9810  -17.4331
            2   C8y C    20.9810  -18.8322
            3   C8x C    22.1994  -16.7335
            4   O2x O    19.6460  -16.9959
            5   C8x C    22.1994  -19.5377
            6   O2x O    19.6401  -19.2694
            7   C8y C    23.4061  -17.4331
            8   C1x C    18.8241  -18.1326
            9   C8x C    23.4061  -18.8322
            10  C1b C    24.6129  -16.7335
            11  C1b C    25.8256  -17.4331
            12  C1c C    27.0381  -16.7335
            13  N1b N    28.2457  -17.4312
            14  N1a N    29.4538  -16.7343
            15  C1a C    27.0384  -15.3386
            16  X   Cl   31.4718  -19.2008
BOND        16
            1     1   4 1
            2     2   5 2
            3     2   6 1
            4     3   7 1
            5     4   8 1
            6     5   9 1
            7     7  10 1
            8    10  11 1
            9    11  12 1
            10    6   8 1
            11    7   9 2
            12   12  13 1
            13    1   2 1
            14   13  14 1
            15   12  15 1
            16    1   3 2

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