KEGG   DRUG: D01888Help
Entry
D01888                      Drug                                   

Name
Safrazine hydrochloride (JAN)
Formula
C11H16N2O2. HCl
Exact mass
244.0979
Mol weight
244.7179
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Comment
withdrawal drug
Target
monoamine oxidase (MAO) inhibitor [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Structure map
Catecholamine transferase inhibitors
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase (MAO)
    Safrazine
     D01888  Safrazine hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
7296-30-2
PubChem: 
LigandBox: 
KCF data Show

ATOM        16
            1   C8y C    20.9810  -17.4331
            2   C8y C    20.9810  -18.8322
            3   C8x C    22.1994  -16.7335
            4   O2x O    19.6460  -16.9959
            5   C8x C    22.1994  -19.5377
            6   O2x O    19.6401  -19.2694
            7   C8y C    23.4061  -17.4331
            8   C1x C    18.8241  -18.1326
            9   C8x C    23.4061  -18.8322
            10  C1b C    24.6129  -16.7335
            11  C1b C    25.8256  -17.4331
            12  C1c C    27.0381  -16.7335
            13  N1b N    28.2457  -17.4312
            14  N1a N    29.4538  -16.7343
            15  C1a C    27.0384  -15.3386
            16  X   Cl   31.4718  -19.2008
BOND        16
            1     1   4 1
            2     2   5 2
            3     2   6 1
            4     3   7 1
            5     4   8 1
            6     5   9 1
            7     7  10 1
            8    10  11 1
            9    11  12 1
            10    6   8 1
            11    7   9 2
            12   12  13 1
            13    1   2 1
            14   13  14 1
            15   12  15 1
            16    1   3 2

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