| Entry |
|
|---|
| Name |
Enprostil (JAN/USAN/INN);
Camleed (TN) |
|---|
| Formula |
C23H28O6
|
|---|
| Exact mass |
400.1886
|
|---|
| Mol weight |
400.4648
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG01961 Prostaglandin derivative
DG01959 Prostaglandin E2 derivative
Gastrointestinal agent
DG01975 Agents for peptic ulcer
|
|---|
| Remark |
|
|---|
| Efficacy |
Antisecretory (gastric acid), Anti-ulcerative, Prostaglandin receptor agonist |
|---|
| Comment |
Prostaglandin derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07228 | Eicosanoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BB Prostaglandins
A02BB02 Enprostil
D01891 Enprostil (JAN/USAN/INN)
Drug groups [BR:br08330]
Hormonal agent
DG01961 Prostaglandin derivative
DG01959 Prostaglandin E2 derivative
D01891 Enprostil
Gastrointestinal agent
DG01975 Agents for peptic ulcer
D01891 Enprostil
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Prostaglandin
PTGER2
D01891 Enprostil (JAN/USAN/INN)
PTGER3
D01891 Enprostil (JAN/USAN/INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 29
1 C1y C 24.2658 -14.2131
2 C1y C 24.2599 -15.6263
3 C5x C 22.9226 -13.7809
4 C1b C 25.4805 -13.5063
5 C1y C 22.9400 -16.0585
6 C2b C 25.4805 -16.3214
7 C1x C 22.0991 -14.9255
8 O5x O 22.4846 -12.4493
9 C2b C 26.6953 -14.2131
10 O1a O 22.5195 -17.3960
11 C2b C 26.6953 -15.6263
12 C1c C 27.9159 -16.3214
13 C1b C 29.1306 -15.6263
14 O1a O 27.9159 -17.7288
15 O2a O 30.3453 -16.3214
16 C8y C 30.3507 -17.7186
17 C8x C 31.5617 -18.4098
18 C8x C 31.5671 -19.8071
19 C8x C 30.3597 -20.5103
20 C8x C 29.1469 -19.8164
21 C8x C 29.1416 -18.4191
22 C0 C 28.0911 -14.2141
23 C2b C 29.4883 -14.2141
24 C1b C 30.6950 -13.5224
25 C1b C 31.9018 -14.2211
26 C7a C 33.1084 -13.5296
27 O7a O 34.3151 -14.2282
28 O6a O 33.1114 -12.1324
29 C1a C 35.5261 -13.5311
BOND 30
1 13 15 1
2 5 7 1
3 15 16 1
4 1 2 1
5 1 3 1
6 1 4 1 #Down
7 2 5 1
8 2 6 1 #Up
9 16 17 2
10 17 18 1
11 18 19 2
12 19 20 1
13 20 21 2
14 21 16 1
15 3 7 1
16 9 22 2
17 3 8 2
18 22 23 2
19 4 9 1
20 23 24 1
21 5 10 1 #Down
22 24 25 1
23 6 11 2
24 25 26 1
25 11 12 1
26 26 27 1
27 12 13 1
28 26 28 2
29 12 14 1 #Down
30 27 29 1
|
|---|
