KEGG   DRUG: D01895Help
Entry
D01895                      Drug                                   

Name
Tripamide (JAN/USAN/INN);
Normonal (TN)
Formula
C16H20ClN3O3S
Exact mass
369.0914
Mol weight
369.8663
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive;
Diuretic
Remark
Therapeutic category: 
Comment
Loop diuretics
Target
Na-K-Cl cotransporter 1 inhibitor [HSA:6557] [KO:K14425];
Na-K-Cl cotransporter 2 inhibitor [HSA:6558] [KO:K10951]
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Ion transporter inhibitors
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D01895  Tripamide (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A1
     Tripamide
      D01895  Tripamide (JAN/USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
73803-48-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C1x C    21.5425  -13.5829
            2   N1y N    20.5383  -12.6368
            3   C1x C    21.1246  -11.3715
            4   N1b N    19.2906  -13.3333
            5   C5a C    18.1065  -12.6309
            6   C8y C    16.8993  -13.3041
            7   O5a O    18.1181  -11.2494
            8   C8x C    15.6979  -12.6309
            9   C8x C    16.8642  -14.6798
            10  C8y C    14.5137  -13.3333
            11  C8x C    15.7268  -15.3936
            12  C8y C    14.5196  -14.7146
            13  S4a S    13.3008  -12.6600
            14  X   Cl   13.3356  -15.4285
            15  N1a N    14.1307  -11.5282
            16  O3c O    12.3780  -13.9542
            17  O3c O    12.0471  -11.9750
            18  C1y C    22.5003  -11.5514
            19  C1y C    22.7504  -12.9134
            20  C1y C    24.0552  -13.3780
            21  C1x C    25.1097  -12.4802
            22  C1x C    24.8596  -11.1182
            23  C1y C    23.5547  -10.6536
            24  C1x C    24.3292  -11.9170
BOND        27
            1     6   9 2
            2     8  10 2
            3     9  11 1
            4    10  12 1
            5    10  13 1
            6    12  14 1
            7    13  15 1
            8    13  16 2
            9    13  17 2
            10    3  18 1
            11   11  12 2
            12    1   2 1
            13    1  19 1
            14    2   3 1
            15    2   4 1
            16    4   5 1
            17   18  19 1
            18   19  20 1
            19   20  21 1
            20   21  22 1
            21   22  23 1
            22   23  18 1
            23    5   6 1
            24   23  24 1 #Up
            25   20  24 1 #Up
            26    5   7 2
            27    6   8 1

» Japanese version   » Back

DBGET integrated database retrieval system