KEGG   DRUG: TripamideHelp
Entry
D01895                      Drug                                   

Name
Tripamide (JAN/USAN/INN);
Normonal (TN)
Formula
C16H20ClN3O3S
Exact mass
369.0914
Mol weight
369.8663
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
Activity
Antihypertensive, Na-K-Cl cotransporter inhibitor
Target
Na-K-Cl cotransporter 1 [HSA:6557] [KO:K14425];
Na-K-Cl cotransporter 2 [HSA:6558] [KO:K10951]
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Ion transporter inhibitors
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D01895  Tripamide (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A1
     Tripamide
      D01895  Tripamide (JAN/USAN/INN)
Cardiovascular agents [br08364.html]
 Antihypertensives
  D01895
BRITE hierarchy
Other DBs
CAS: 
73803-48-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C1x C    15.6800  -16.9400
            2   N1y N    16.7300  -16.0300
            3   C1x C    16.1000  -14.7000
            4   N1b N    17.9200  -16.6600
            5   C5a C    19.1100  -15.9600
            6   C8y C    20.3700  -16.6600
            7   O5a O    19.1100  -14.6300
            8   C8x C    21.5600  -15.9600
            9   C8x C    20.3700  -18.0600
            10  C8y C    22.7500  -16.6600
            11  C8x C    21.4900  -18.7600
            12  C8y C    22.7500  -18.0600
            13  S4a S    23.9400  -16.0300
            14  X   Cl   23.8700  -18.7600
            15  O3c O    23.1000  -14.9100
            16  O3c O    24.8500  -17.2900
            17  N1a N    25.2000  -15.3300
            18  C1y C    14.7700  -14.9100
            19  C1y C    14.4900  -16.2400
            20  C1y C    13.1600  -16.7300
            21  C1x C    12.1100  -15.8200
            22  C1x C    12.3900  -14.4900
            23  C1y C    13.7200  -14.0000
            24  C1x C    12.8800  -15.2600
BOND        27
            1     6   9 2
            2     8  10 2
            3     9  11 1
            4    10  12 1
            5    10  13 1
            6    12  14 1
            7    13  15 2
            8    13  16 2
            9    13  17 1
            10    3  18 1
            11   11  12 2
            12    1   2 1
            13    1  19 1
            14    2   3 1
            15    2   4 1
            16    4   5 1
            17   18  19 1
            18   19  20 1
            19   20  21 1
            20   21  22 1
            21   22  23 1
            22   23  18 1
            23    5   6 1
            24   23  24 1 #Down
            25   20  24 1 #Down
            26    5   7 2
            27    6   8 1

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