| Entry |
|
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| Name |
Cilostazol (JP16/USAN/INN);
Pletal (TN)
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| Product |
|
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| Generic |
CILOSTAZOL (Apotex Corp.), CILOSTAZOL (Breckenridge Pharmaceutical), CILOSTAZOL (Bryant Ranch Prepack), CILOSTAZOL (Cardinal Health), CILOSTAZOL (Corepharma LLC.), CILOSTAZOL (Eon Labs), CILOSTAZOL (Golden State Medical Supply), CILOSTAZOL (Golden State Medical Supply), CILOSTAZOL (Mylan Pharmaceuticals), CILOSTAZOL (NCS HealthCare of KY), CILOSTAZOL (NCS HealthCare of KY), CILOSTAZOL (Physicians Total Care), CILOSTAZOL (Roxane Laboratories), CILOSTAZOL (STAT RX USA LLC), CILOSTAZOL (Teva Pharmaceuticals USA), CILOSTAZOL (Teva Pharmaceuticals USA), CILOSTAZOL (UDL Laboratories) |
|---|
| Formula |
C20H27N5O2
|
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| Exact mass |
369.2165
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| Mol weight |
369.4607
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| Structure |
     |
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| Activity |
Vasodilator;
Inhibitor [platelet];
Antithrombotic
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| Remark |
Therapeutic category: ATC code: |
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| Target |
phosphodiesterase III inhibitor [HSA: 5139 5140] [KO: K13296]; adenosine uptake inhibitor |
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| Pathway |
|
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576], CYP2D6 [HSA: 1565], CYP2C19 [HSA: 1557]
|
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| Interaction |
CYP inhibition: CYP3A [KO: K07424]
 |
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| Structure map |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
33 Blood and body fluid agents
339 Miscellaneous
3399 Others
D01896 Cilostazol (JP16/USAN/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AC Platelet aggregation inhibitors excl. heparin
B01AC23 Cilostazol
D01896 Cilostazol (JP16/USAN/INN)
USP drug classification [BR:br08302]
Blood Products / Modifiers / Volume Expanders
Platelet Modifying Agents
Phosphodiesterase III / Adenosine Uptake Inhibitors
Cilostazol
D01896 Cilostazol (JP16/USAN/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases
phosphodiesterase (PDE) III [HSA:5139 5140] [KO:K13296]
Cilostazol [ATC:B01AC23]
D01896 Cilostazol (JP16/USAN/INN)
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| Other DBs |
CAS: 73963-72-1 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 27
1 C1y C 21.6291 -13.6161
2 C1x C 21.6291 -15.0158
3 C1x C 20.4140 -15.7157
4 C1x C 19.2060 -15.0158
5 C1x C 19.2060 -13.6161
6 C1x C 20.4140 -12.9162
7 N4y N 22.8410 -12.9155
8 C8y C 22.8310 -11.5237
9 N5x N 24.1537 -11.0795
10 N5x N 24.9846 -12.2002
11 N5x N 24.1756 -13.3370
12 C8y C 13.1531 -11.4954
13 C8y C 13.1600 -12.9021
14 N1x N 11.9445 -13.6081
15 C5x C 10.7217 -12.9144
16 C1x C 10.7146 -11.5078
17 C1x C 11.9303 -10.7947
18 C8y C 15.5755 -11.5086
19 C8x C 15.5771 -12.9086
20 C8x C 14.3572 -13.6076
21 C8x C 14.3592 -10.7940
22 O5x O 9.5059 -13.6203
23 O2a O 16.7868 -10.8096
24 C1b C 17.9956 -11.5095
25 C1b C 19.2045 -10.8167
26 C1b C 20.4133 -11.5166
27 C1b C 21.6222 -10.8239
BOND 30
1 1 7 1
2 1 2 1
3 2 3 1
4 3 4 1
5 4 5 1
6 7 8 1
7 8 9 2
8 9 10 1
9 13 14 1
10 18 19 1
11 19 20 2
12 20 13 1
13 12 21 1
14 21 18 2
15 14 15 1
16 15 16 1
17 16 17 1
18 17 12 1
19 12 13 2
20 15 22 2
21 10 11 2
22 18 23 1
23 11 7 1
24 23 24 1
25 5 6 1
26 24 25 1
27 6 1 1
28 25 26 1
29 26 27 1
30 27 8 1
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