| Entry |
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| Name |
Haloperidol decanoate (JAN/USAN);
Halomonth (TN)
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| Product |
|
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| Generic |
|
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| Formula |
C31H41ClFNO3
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| Exact mass |
529.2759
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| Mol weight |
530.1135
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| Structure |
     |
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| Activity |
Antipsychotic
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| Remark |
Therapeutic category: ATC code: |
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| Target |
dopamine D2-receptor antagonist [HSA: 1813] [KO: K04145] |
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| Pathway |
|
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| Metabolism |
Enzyme: CYP2D6 [HSA: 1565], CYP3A4 [HSA: 1576], CYP1A2 [HSA: 1544]
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| Interaction |
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| Structure map |
| Butyrophenones | | Butyrophenone family | | Dopamine receptor agonists/antagonists |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1179 Others
D01898 Haloperidol decanoate (JAN/USAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AD Butyrophenone derivatives
N05AD01 Haloperidol
D01898 Haloperidol decanoate (JAN/USAN)
USP drug classification [BR:br08302]
Antipsychotics
1st Generation/Typical
Haloperidol
D01898 Haloperidol decanoate (JAN/USAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
dopamine D2-receptor [HSA:1813] [KO:K04145]
Haloperidol [ATC:N05AD01]
D01898 Haloperidol decanoate (JAN/USAN)
 |
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| Other DBs |
CAS: 74050-97-8 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 37
1 C1b C 16.3100 -17.5700
2 C1b C 17.5000 -16.8700
3 C1b C 18.6900 -17.5700
4 N1y N 19.9500 -16.8700
5 C1x C 19.9500 -15.4700
6 C1x C 21.1400 -17.5700
7 C1x C 21.1400 -14.7700
8 C1x C 22.3300 -16.8700
9 C1z C 22.3300 -15.4700
10 C8y C 23.5900 -14.7700
11 C8x C 23.5900 -13.4400
12 C8x C 24.7800 -15.4700
13 C8x C 24.7800 -12.7400
14 C8x C 25.9700 -14.8400
15 C8y C 25.9700 -13.4400
16 X Cl 27.1600 -12.7400
17 C5a C 15.0500 -16.8700
18 C8y C 13.7900 -17.5700
19 O5a O 15.0500 -15.4000
20 C8x C 13.7900 -18.9700
21 C8x C 12.6000 -19.6700
22 C8y C 11.3400 -18.9700
23 C8x C 11.3400 -17.5700
24 C8x C 12.6000 -16.8700
25 X F 10.0800 -19.6700
26 O7a O 23.5200 -16.1700
27 C7a C 23.5200 -17.5700
28 C1b C 24.7100 -18.2700
29 O6a O 22.2600 -18.2700
30 C1b C 25.9000 -17.6400
31 C1b C 27.0900 -18.2700
32 C1b C 28.2800 -17.6400
33 C1b C 29.4700 -18.2700
34 C1b C 30.8000 -17.6400
35 C1b C 31.9900 -18.2700
36 C1b C 33.1800 -17.6400
37 C1a C 34.3700 -18.2700
BOND 39
1 1 17 1
2 1 2 1
3 17 18 1
4 2 3 1
5 17 19 2
6 3 4 1
7 4 5 1
8 4 6 1
9 5 7 1
10 6 8 1
11 18 20 1
12 20 21 2
13 21 22 1
14 22 23 2
15 23 24 1
16 24 18 2
17 7 9 1
18 22 25 1
19 9 10 1
20 10 11 1
21 10 12 2
22 11 13 2
23 12 14 1
24 13 15 1
25 15 16 1
26 8 9 1
27 14 15 2
28 9 26 1
29 26 27 1
30 27 28 1
31 27 29 2
32 28 30 1
33 30 31 1
34 31 32 1
35 32 33 1
36 33 34 1
37 34 35 1
38 35 36 1
39 36 37 1
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