| Entry |
|
|---|
| Name |
Alacepril (JP16/INN);
Cetapril (TN)
|
|---|
| Formula |
C20H26N2O5S
|
|---|
| Exact mass |
406.1562
|
|---|
| Mol weight |
406.4958
|
|---|
| Structure |
     |
|---|
| Activity |
Antihypertensive
|
|---|
| Remark |
|
|---|
| Target |
angiotensin-converting enzyme (ACE) inhibitor [HSA: 1636] [KO: K01283] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| Renin-angiotensin system inhibitors |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2144 Angiotensin converting enzyme inhibitors
D01900 Alacepril (JP16/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases
angiotensin-converting enzyme (ACE) [HSA:1636] [KO:K01283]
Alacepril
D01900 Alacepril (JP16/INN)
 |
|---|
| Other DBs |
CAS: 74258-86-9 PubChem: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 28
1 C1x C 20.1587 -20.1899
2 C1y C 20.5950 -18.8575
3 N1y N 19.4579 -18.0306
4 C1x C 18.3208 -18.8575
5 C1x C 18.7570 -20.1899
6 C5a C 19.4577 -16.6288
7 O5a O 20.6717 -15.9279
8 C1c C 18.2401 -15.9351
9 C1b C 17.0295 -16.6359
10 S2a S 15.8189 -15.9420
11 C5a C 14.6084 -16.6429
12 C1a C 13.3978 -15.9492
13 C5a C 21.8012 -18.1509
14 N1b N 23.0118 -18.8448
15 C1c C 24.2223 -18.1439
16 C1b C 25.4329 -18.8376
17 C8y C 26.6435 -18.1368
18 O5a O 21.7944 -16.7491
19 C6a C 24.2193 -16.7421
20 O6a O 25.4315 -16.0385
21 O6a O 23.0038 -16.0438
22 C8x C 27.8557 -18.8347
23 C8x C 29.0663 -18.1339
24 C8x C 29.0646 -16.7350
25 C8x C 27.8523 -16.0370
26 C8x C 26.6418 -16.7379
27 C1a C 18.2353 -14.5333
28 O5a O 14.6114 -18.0447
BOND 29
1 13 14 1
2 6 7 2
3 14 15 1
4 2 3 1
5 15 16 1
6 6 8 1
7 16 17 1
8 3 4 1
9 13 18 2
10 8 9 1
11 15 19 1 #Down
12 4 5 1
13 19 20 1
14 9 10 1
15 19 21 2
16 5 1 1
17 10 11 1
18 11 12 1
19 3 6 1
20 17 22 2
21 22 23 1
22 23 24 2
23 24 25 1
24 25 26 2
25 26 17 1
26 2 13 1 #Down
27 8 27 1 #Up
28 1 2 1
29 11 28 2
|
|---|
