KEGG   DRUG: D01900Help
Entry
D01900                      Drug                                   

Name
Alacepril (JP16/INN);
Cetapril (TN)
Formula
C20H26N2O5S
Exact mass
406.1562
Mol weight
406.4958
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
Therapeutic category: 
Comment
prodrug, active substance: Desacetyl-alacepril
Target
angiotensin-converting enzyme (ACE) inhibitor [HSA:1636] [KO:K01283]
  Pathway
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Structure map
Renin-angiotensin system inhibitors
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2144  Angiotensin converting enzyme inhibitors
     D01900  Alacepril (JP16/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   angiotensin-converting enzyme (ACE)
    Alacepril
     D01900  Alacepril (JP16/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01900  Alacepril
  D01900  Alacepril tablets
BRITE hierarchy
Other DBs
CAS: 
74258-86-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C1x C    20.1587  -20.1899
            2   C1y C    20.5950  -18.8575
            3   N1y N    19.4579  -18.0306
            4   C1x C    18.3208  -18.8575
            5   C1x C    18.7570  -20.1899
            6   C5a C    19.4577  -16.6288
            7   O5a O    20.6717  -15.9279
            8   C1c C    18.2401  -15.9351
            9   C1b C    17.0295  -16.6359
            10  S2a S    15.8189  -15.9420
            11  C5a C    14.6084  -16.6429
            12  C1a C    13.3978  -15.9492
            13  C5a C    21.8012  -18.1509
            14  N1b N    23.0118  -18.8448
            15  C1c C    24.2223  -18.1439
            16  C1b C    25.4329  -18.8376
            17  C8y C    26.6435  -18.1368
            18  O5a O    21.7944  -16.7491
            19  C6a C    24.2193  -16.7421
            20  O6a O    25.4315  -16.0385
            21  O6a O    23.0038  -16.0438
            22  C8x C    27.8557  -18.8347
            23  C8x C    29.0663  -18.1339
            24  C8x C    29.0646  -16.7350
            25  C8x C    27.8523  -16.0370
            26  C8x C    26.6418  -16.7379
            27  C1a C    18.2353  -14.5333
            28  O5a O    14.6114  -18.0447
BOND        29
            1    13  14 1
            2     6   7 2
            3    14  15 1
            4     2   3 1
            5    15  16 1
            6     6   8 1
            7    16  17 1
            8     3   4 1
            9    13  18 2
            10    8   9 1
            11   15  19 1 #Down
            12    4   5 1
            13   19  20 1
            14    9  10 1
            15   19  21 2
            16    5   1 1
            17   10  11 1
            18   11  12 1
            19    3   6 1
            20   17  22 2
            21   22  23 1
            22   23  24 2
            23   24  25 1
            24   25  26 2
            25   26  17 1
            26    2  13 1 #Down
            27    8  27 1 #Up
            28    1   2 1
            29   11  28 2

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