KEGG   DRUG: D01907Help
Entry
D01907                      Drug                                   

Name
Fludarabine phosphate (JAN/USP);
Fludara (TN)
Product
  Generic
Formula
C10H13FN5O7P
Exact mass
365.0537
Mol weight
365.2117
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antineoplastic [DS:H00005 H00011]
Remark
Therapeutic category: 
ATC code: 
Comment
DNA synthesis inhibitor
purine analogue
arabinofuranosyl derivative
prodrug, active substance: Fludarabine [DR:D07966]
Interaction
Drug interaction
Structure map
Antineoplastics - antimetabolic agents
Antiviral agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   422  Antimetabolites
    4229  Others
     D01907  Fludarabine phosphate (JAN/USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01B ANTIMETABOLITES
    L01BB Purine analogues
     L01BB05 Fludarabine
      D01907  Fludarabine phosphate (JAN/USP)
USP drug classification [BR:br08302]
 Antineoplastics
  Antineoplastics, Other
   Fludarabine
    D01907  Fludarabine phosphate (JAN/USP)
Antineoplastics [BR:br08308]
 Antimetabolites
  Purine analogues
   Fludarabine [ATC:L01BB05]
    D01907  Fludarabine phosphate (JAN/USP)
BRITE hierarchy
Other DBs
CAS: 
75607-67-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C1y C    11.4800  -11.6200
            2   C1y C    12.8800  -11.6200
            3   C1y C    13.3126  -10.2885
            4   O2x O    12.1800   -9.4656
            5   C1y C    11.0474  -10.2885
            6   O1a O    10.7800  -12.8324
            7   O1a O    13.5800  -12.8324
            8   N5x N    15.7375  -11.6885
            9   C8y C    15.7375  -10.2885
            10  N4y N    14.5251   -9.5885
            11  C1b C     9.8349   -9.5885
            12  O2b O     8.6225  -10.2885
            13  C8y C    16.9499  -12.3885
            14  N5x N    18.1624  -11.6885
            15  C8y C    18.1624  -10.2885
            16  C8y C    16.9499   -9.5885
            17  N5x N    16.6589   -8.2191
            18  C8x C    15.2665   -8.0727
            19  N1a N    19.3497   -9.6027
            20  X   F    16.9499  -13.7900
            21  P1b P     7.2225  -10.2885
            22  O1c O     5.8225  -10.2885
            23  O1c O     7.2225   -8.8901
            24  O1c O     7.2225  -11.6899
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     1   6 1 #Down
            7     2   7 1 #Up
            8     8   9 1
            9     9  10 1
            10    3  10 1 #Up
            11    5  11 1 #Up
            12   11  12 1
            13    8  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17    9  16 2
            18   16  17 1
            19   17  18 2
            20   18  10 1
            21   15  19 1
            22   13  20 1
            23   12  21 1
            24   21  22 1
            25   21  23 2
            26   21  24 1

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