KEGG   DRUG: D01943Help
Entry
D01943                      Drug                                   

Name
Potassium canrenoate (JP16);
Canrenoate potassium (USAN);
Soldactone (TN)
Formula
C22H29O4. K
Exact mass
396.1703
Mol weight
396.5616
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Aldosterone antagonist
Remark
Therapeutic category: 
ATC code: 
Target
mineralocorticoid receptor antagonist [HSA:4306] [KO:K08555]
  Pathway
hsa04960  Aldosterone-regulated sodium reabsorption  
 
Interaction
Drug interaction
Structure map
Glucocorticoid and meneralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C03 DIURETICS
   C03D POTASSIUM-SPARING AGENTS
    C03DA Aldosterone antagonists
     C03DA02 Potassium canrenoate
      D01943  Potassium canrenoate (JP16); Canrenoate potassium (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   213  Diuretics
    2133  Antialdosterones
     D01943  Potassium canrenoate (JP16); Canrenoate potassium (USAN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    mineralocorticoid receptor
     Potassium canrenoate
      D01943  Canrenoate potassium (USAN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01943  Potassium canrenoate
BRITE hierarchy
Other DBs
CAS: 
2181-04-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C1x C    12.3998  -16.4177
            2   C5x C    12.3998  -17.7762
            3   C2x C    13.5763  -18.4554
            4   C2y C    14.7527  -17.7762
            5   C1z C    14.7527  -16.4177
            6   C1x C    13.5763  -15.7384
            7   C2x C    15.9292  -18.4554
            8   C2x C    17.1057  -17.7762
            9   C1y C    17.1057  -16.4177
            10  C1y C    15.9292  -15.7384
            11  C1y C    18.2822  -15.7384
            12  C1z C    18.2822  -14.3800
            13  C1x C    17.1057  -13.7007
            14  C1x C    15.9292  -14.3800
            15  C1x C    20.6351  -15.7384
            16  C1x C    20.6351  -14.3800
            17  C1z C    19.4587  -13.7007
            18  O1a O    19.4639  -12.3422
            19  C1b C    20.6412  -13.0215
            20  C1b C    21.9997  -13.0215
            21  C6a C    22.6910  -11.8239
            22  O6a O    24.0748  -11.8237 #-
            23  O6a O    21.9819  -10.5959
            24  C1a C    18.2834  -12.9821
            25  C1a C    14.7338  -15.0371
            26  O5x O    11.1783  -18.4813
            27  Z   K    26.0167  -11.9000 #+
BOND        29
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21   17  18 1 #Up
            22   17  19 1 #Down
            23   19  20 1
            24   20  21 1
            25   21  22 1
            26   21  23 2
            27   12  24 1 #Up
            28    5  25 1 #Up
            29    2  26 2

» Japanese version   » Back

DBGET integrated database retrieval system