KEGG   DRUG: D01946Help
Entry
D01946                      Drug                                   

Name
Oxitropium bromide (JAN/INN);
Tersigan (TN)
Formula
C19H26NO4. Br
Exact mass
411.1045
Mol weight
412.318
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator [DS:H00079]
Remark
Therapeutic category: 
ATC code: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion  
 
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   225  Bronchodilators
    2259  Others
     D01946  Oxitropium bromide (JAN/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BB Anticholinergics
     R03BB02 Oxitropium bromide
      D01946  Oxitropium bromide (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
     Oxitropium bromide [ATC:R03BB02]
      D01946  Oxitropium bromide (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
30286-75-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C1y C    14.1638  -11.1808
            2   C1y C    14.4919  -10.0091
            3   C1y C    15.3355  -10.8996
            4   C1y C    15.6636   -9.7279
            5   N2y N    14.3982   -8.4156 #+
            6   C1x C    17.2102  -10.8996
            7   C1x C    16.9290   -9.7279
            8   C1y C    18.2413  -11.4620
            9   O7a O    19.3193  -12.3525
            10  C7a C    20.5379  -12.3525
            11  C1c C    21.1472  -11.2745
            12  O6a O    21.1472  -13.4773
            13  C8y C    22.3658  -11.2745
            14  C1b C    20.5379  -10.2434
            15  O1a O    21.1472   -9.1655
            16  C8x C    23.0720  -12.4982
            17  C8x C    24.4720  -12.4985
            18  C8x C    25.1722  -11.2862
            19  C8x C    24.4661  -10.0625
            20  C8x C    23.0661  -10.0622
            21  C1a C    13.6491   -7.2314
            22  C1b C    13.1689   -9.0283
            23  C1a C    11.9962   -8.2518
            24  O2x O    12.9533  -10.4573
            25  X   Br   18.2000   -7.4200 #-
BOND        27
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 1 #Down
            13   11  14 1
            14   14  15 1
            15    4   5 1
            16    7   8 1
            17   13  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   13  20 1
            23    5  21 1
            24    5  22 1
            25   22  23 1
            26    1  24 1
            27    2  24 1

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