KEGG   DRUG: D01946Help
Entry
D01946                      Drug                                   

Name
Oxitropium bromide (JAN/INN);
Tersigan (TN)
Formula
C19H26NO4. Br
Exact mass
411.1045
Mol weight
412.318
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator [DS:H00079]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion  
 
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BB Anticholinergics
     R03BB02 Oxitropium bromide
      D01946  Oxitropium bromide (JAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   225  Bronchodilators
    2259  Others
     D01946  Oxitropium bromide (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Oxitropium bromide
      D01946  Oxitropium bromide (JAN/INN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D01946  Oxitropium bromide (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
30286-75-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C1y C    14.1638  -11.1808
            2   C1y C    14.4919  -10.0091
            3   C1y C    15.3355  -10.8996
            4   C1y C    15.6636   -9.7279
            5   N2y N    14.3982   -8.4156 #+
            6   C1x C    17.2102  -10.8996
            7   C1x C    16.9290   -9.7279
            8   C1y C    18.2413  -11.4620
            9   O7a O    19.3193  -12.3525
            10  C7a C    20.5379  -12.3525
            11  C1c C    21.1472  -11.2745
            12  O6a O    21.1472  -13.4773
            13  C8y C    22.3658  -11.2745
            14  C1b C    20.5379  -10.2434
            15  O1a O    21.1472   -9.1655
            16  C8x C    23.0720  -12.4982
            17  C8x C    24.4720  -12.4985
            18  C8x C    25.1722  -11.2862
            19  C8x C    24.4661  -10.0625
            20  C8x C    23.0661  -10.0622
            21  C1a C    13.6491   -7.2314
            22  C1b C    13.1689   -9.0283
            23  C1a C    11.9962   -8.2518
            24  O2x O    12.9533  -10.4573
            25  X   Br   18.2000   -7.4200 #-
BOND        27
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 1 #Down
            13   11  14 1
            14   14  15 1
            15    4   5 1
            16    7   8 1
            17   13  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   13  20 1
            23    5  21 1
            24    5  22 1
            25   22  23 1
            26    1  24 1
            27    2  24 1

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