KEGG   DRUG: D01952Help
Entry
D01952                      Drug                                   
Name
L-Methylephedrine hydrochloride (JAN)
Formula
C11H17NO. HCl
Exact mass
215.1077
Mol weight
215.7197
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator [DS:H00079]
Target
alpha1-adrenergic receptor agonist [HSA:146 147 148] [KO:K04137 K04136 K04135];
alpha2-adrenergic receptor agonist [HSA:150 151 152] [KO:K04138 K04139 K04140];
beta1-adrenergic receptor agonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor agonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
     Methylephedrine
      D01952  L-Methylephedrine hydrochloride (JAN)
    alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140]
     Methylephedrine
      D01952  L-Methylephedrine hydrochloride (JAN)
    beta1-adrenergic receptor [HSA:153] [KO:K04141]
     Methylephedrine
      D01952  L-Methylephedrine hydrochloride (JAN)
    beta2-adrenergic receptor [HSA:154] [KO:K04142]
     Methylephedrine
      D01952  L-Methylephedrine hydrochloride (JAN)
    beta3-adrenergic receptor [HSA:155] [KO:K04143]
     Methylephedrine
      D01952  L-Methylephedrine hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
38455-90-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   C8x C    26.1800  -17.1500
            2   C8x C    26.1800  -18.5500
            3   C8x C    27.3700  -19.3200
            4   C8x C    28.5600  -18.5500
            5   C8y C    28.5600  -17.1500
            6   C8x C    27.3700  -16.4500
            7   C1c C    29.8200  -16.4500
            8   C1c C    31.0100  -17.1500
            9   N1c N    32.2000  -16.4500
            10  C1a C    33.4600  -17.1500
            11  C1a C    31.0100  -18.5500
            12  O1a O    29.8200  -15.0500
            13  C1a C    32.2000  -15.0500
            14  X   Cl   37.9400  -16.9400
BOND        13
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    8  11 1 #Up
            12    7  12 1 #Up
            13    9  13 1

» Japanese version   » Back
DBGET integrated database retrieval system