KEGG   DRUG: D01972Help
Entry
D01972                      Drug                                   

Name
Lanatoside C (JP16/INN);
Digilanogen C (TN)
Formula
C49H76O20
Exact mass
984.493
Mol weight
985.1157
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Digitalis lanata [TAX:49450], Digitalis purpurea [TAX:4164]
Activity
Caediotonic
Remark
ATC code: 
Target
Na+,K+-ATPase inhibitor [HSA:476 477 478 480 23439 481 482 483] [KO:K01539 K01540]
  Pathway
hsa04260  Cardiac muscle contraction  
 
Interaction
Drug interaction
Structure map
Ion transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01A CARDIAC GLYCOSIDES
    C01AA Digitalis glycosides
     C01AA06 Lanatoside C
      D01972  Lanatoside C (JP16/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   sodium/potassium-transporting ATPase
    Lanatoside C
     D01972  Lanatoside C (JP16/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01972  Lanatoside C
  D01972  Lanatoside C tablets
BRITE hierarchy
Other DBs
CAS: 
17575-22-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        69
            1   C1y C     7.4232  -18.4918
            2   C1y C     7.4232  -19.8777
            3   C1y C     8.6233  -20.5706
            4   O2x O     9.8234  -19.8777
            5   C1y C     9.8234  -18.4918
            6   C1y C     8.6233  -17.7989
            7   O2a O    11.0249  -17.7981
            8   C1y C    12.2265  -18.4918
            9   C1y C    12.2265  -19.8777
            10  C1x C    13.4266  -20.5706
            11  C1y C    14.6268  -19.8777
            12  O2x O    14.6268  -18.4918
            13  C1y C    13.4266  -17.7989
            14  O2a O    16.1798  -20.5706
            15  C1y C    17.5898  -19.8777
            16  C1y C    18.7913  -20.5713
            17  O2x O    19.9915  -19.8785
            18  C1y C    19.9915  -18.4925
            19  C1x C    18.7899  -17.7989
            20  C1y C    17.5898  -18.4918
            21  O2a O    21.3339  -17.7989
            22  C1y C    22.8840  -18.4918
            23  C1y C    22.8840  -19.8777
            24  C1x C    24.0843  -20.5706
            25  C1y C    25.2845  -19.8777
            26  O2x O    25.2845  -18.4918
            27  C1y C    24.0843  -17.7989
            28  O2a O    26.4882  -20.5706
            29  C1y C    27.6884  -19.8777
            30  O1a O     8.6233  -16.4130
            31  O1a O     6.2228  -17.7989
            32  O1a O     6.2228  -20.5706
            33  C1b C     8.6233  -21.9563
            34  O1a O     7.4237  -22.6489
            35  O7a O    11.0267  -20.5703
            36  C7a C    11.0277  -21.9615
            37  C1a C    12.2310  -22.6552
            38  O6a O     9.8283  -22.6550
            39  C1a C    13.4266  -16.4180
            40  O1a O    16.3972  -17.8031
            41  C1a C    18.7912  -21.9631
            42  O1a O    21.6875  -20.5686
            43  C1a C    24.0844  -16.4181
            44  C1x C    28.8994  -20.5769
            45  C1y C    30.1000  -19.8837
            46  C1z C    30.1000  -18.4974
            47  C1x C    28.8889  -17.7982
            48  C1x C    27.6884  -18.4913
            49  C1x C    31.3007  -20.5769
            50  C1x C    32.5012  -19.8837
            51  C1y C    32.5012  -18.4974
            52  C1y C    31.3007  -17.8042
            53  C1z C    33.7018  -17.8042
            54  C1z C    33.7018  -16.4179
            55  C1y C    32.5012  -15.7247
            56  C1x C    31.3007  -16.4179
            57  C1x C    36.1029  -17.8042
            58  C1x C    36.1029  -16.4179
            59  C1y C    34.9024  -15.7247
            60  C2y C    34.9024  -14.0585
            61  C1x C    36.0274  -13.2411
            62  O7x O    35.5977  -11.9186
            63  C7x C    34.2071  -11.9186
            64  C2x C    33.7774  -13.2411
            65  O6a O    33.4015  -10.8099
            66  C1a C    33.7020  -15.0304
            67  O1a O    33.7020  -19.1850
            68  O1a O    32.4884  -14.3302
            69  C1a C    30.1077  -17.0844
BOND        77
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Down
            8     8   7 1 #Down
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    8  13 1
            15   11  14 1 #Up
            16   15  14 1 #Up
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   15  20 1
            23   18  21 1 #Down
            24   22  21 1 #Down
            25   22  23 1
            26   23  24 1
            27   24  25 1
            28   25  26 1
            29   26  27 1
            30   22  27 1
            31   25  28 1 #Up
            32   29  28 1 #Up
            33    6  30 1 #Up
            34    1  31 1 #Down
            35    2  32 1 #Up
            36    3  33 1 #Down
            37   33  34 1
            38    9  35 1 #Down
            39   35  36 1
            40   36  37 1
            41   36  38 2
            42   13  39 1 #Up
            43   20  40 1 #Up
            44   16  41 1 #Down
            45   23  42 1 #Down
            46   27  43 1 #Up
            47   29  44 1
            48   44  45 1
            49   45  46 1
            50   46  47 1
            51   47  48 1
            52   29  48 1
            53   45  49 1
            54   49  50 1
            55   50  51 1
            56   51  52 1
            57   46  52 1
            58   51  53 1
            59   53  54 1
            60   54  55 1
            61   55  56 1
            62   52  56 1
            63   53  57 1
            64   57  58 1
            65   58  59 1
            66   54  59 1
            67   59  60 1 #Up
            68   60  61 1
            69   61  62 1
            70   62  63 1
            71   63  64 1
            72   60  64 2
            73   63  65 2
            74   54  66 1 #Up
            75   53  67 1 #Up
            76   55  68 1 #Up
            77   46  69 1 #Up

» Japanese version   » Back

DBGET integrated database retrieval system