KEGG   DRUG: D01982Help
Entry
D01982                      Drug                                   

Name
Tenofovir disoproxil fumarate (JAN/USAN);
Viread (TN)
Product
Formula
C19H30N5O10P. C4H4O4
Exact mass
635.184
Mol weight
635.5149
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiviral [reverse transcriptase inhibitor] [DS:H00406]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Nucleoside reverse transcriptase inhibitor (NRTI)
prodrug, active substance: Tenofovir [DR:D06074]
Target
RNA-directed DNA polymerase inhibitor
Interaction
Drug interaction
Structure map
Antiviral agents
Anti-HIV agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
     J05AF07 Tenofovir disoproxil
      D01982  Tenofovir disoproxil fumarate (JAN/USAN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTI)v
   Tenofovir
    D01982  Tenofovir disoproxil fumarate (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D01982  Tenofovir disoproxil fumarate (JAN/USAN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HIV agents
   Reverse transcriptase inhibitor (RTI)
    Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs)
     Tenofovir
      D01982  Tenofovir disoproxil fumarate (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
202138-50-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        43
            1   C6a C    30.8992  -18.5945
            2   C2b C    32.1576  -19.2936
            3   C2b C    33.3460  -18.5945
            4   C6a C    34.5345  -19.2936
            5   O6a O    35.7928  -18.5945
            6   O6a O    29.7108  -19.2936
            7   O6a O    30.8992  -17.1963
            8   O6a O    34.5345  -20.6917
            9   C8y C    26.5368  -16.8840
            10  C8y C    26.5368  -15.4243
            11  N4y N    25.2162  -17.3012
            12  N5x N    27.7880  -17.5096
            13  N5x N    25.2162  -15.0073
            14  C8y C    27.7880  -14.7987
            15  C8x C    24.3820  -16.1889
            16  C8x C    28.9697  -16.8840
            17  N5x N    28.9697  -15.4243
            18  N1a N    27.7880  -13.4085
            19  C1b C    25.2162  -18.6945
            20  C1c C    24.0155  -19.3876
            21  O2a O    22.8023  -18.6870
            22  C1b C    21.5805  -19.3928
            23  P1b P    20.3622  -18.6904
            24  O2b O    19.1554  -17.9937
            25  O2b O    19.6691  -19.8908
            26  O3b O    21.0616  -17.4784
            27  C1b C    19.1554  -16.5955
            28  C1b C    19.6691  -21.2890
            29  O7a O    17.9438  -15.8681
            30  C7a C    16.7329  -16.5671
            31  O7a O    15.5220  -15.8681
            32  C1c C    14.3112  -16.5671
            33  C1a C    13.1003  -15.8681
            34  O7a O    18.4331  -22.0200
            35  C7a C    17.2222  -21.3209
            36  O7a O    16.0114  -22.0200
            37  C1c C    14.8006  -21.3209
            38  C1a C    13.5897  -22.0200
            39  O6a O    16.7329  -17.9651
            40  C1a C    14.3112  -17.9652
            41  O6a O    17.2222  -19.9230
            42  C1a C    14.8006  -19.9229
            43  C1a C    24.0154  -20.7900
BOND        43
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 1
            5     1   6 1
            6     1   7 2
            7     4   8 2
            8    10  13 1
            9    10  14 1
            10   11  15 1
            11   12  16 2
            12   14  17 2
            13   13  15 2
            14   16  17 1
            15    9  10 2
            16    9  11 1
            17    9  12 1
            18   14  18 1
            19   11  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 1
            23   22  23 1
            24   23  24 1
            25   23  25 1
            26   23  26 2
            27   24  27 1
            28   25  28 1
            29   27  29 1
            30   29  30 1
            31   30  31 1
            32   31  32 1
            33   32  33 1
            34   28  34 1
            35   34  35 1
            36   35  36 1
            37   36  37 1
            38   37  38 1
            39   30  39 2
            40   32  40 1
            41   35  41 2
            42   37  42 1
            43   20  43 1 #Up

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