KEGG   DRUG: D01994Help
Entry
D01994                      Drug                                   

Name
Mosapride citrate hydrate (JP16);
Mosapride citrate dihydrate;
Gasmotin (TN)
Formula
C21H25ClFN3O3. C6H8O7. 2H2O
Exact mass
649.205
Mol weight
650.047
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Peristaltic stimulant
Remark
Same as: 
Therapeutic category: 
Target
5-HT4-receptor agonist [HSA:3360] [KO:K04160]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Drug interaction
Structure map
Serotonin receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   239  Miscellaneous
    2399  Others
     D01994  Mosapride citrate hydrate (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT4-receptor
     Mosapride
      D01994  Mosapride citrate hydrate (JP16)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP3A4
   Mosapride
    D01994  Mosapride citrate hydrate (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01994  Mosapride citrate hydrate
  D01994  Mosapride citrate powder
  D01994  Mosapride citrate tablets
BRITE hierarchy
Other DBs
CAS: 
636582-62-2
PubChem: 
LigandBox: 
KCF data Show

ATOM        44
            1   C1d C    22.8158  -18.4544
            2   C1b C    21.6014  -19.1548
            3   C1b C    24.0300  -19.1548
            4   C6a C    23.5163  -17.2400
            5   O1a O    22.1152  -17.2400
            6   C6a C    20.3871  -18.5010
            7   C6a C    24.0300  -20.5560
            8   O6a O    22.8158  -16.0258
            9   O6a O    24.9173  -17.2400
            10  O6a O    19.1729  -19.2016
            11  O6a O    20.3871  -17.1000
            12  O6a O    25.2443  -21.2565
            13  O6a O    22.8158  -21.2565
            14  O0  O    14.7000  -18.8300
            15  C8y C    10.7100  -13.1600
            16  C8y C    10.7100  -11.7600
            17  C8x C    11.9700  -11.0600
            18  C8y C    13.1600  -11.7600
            19  C8y C    13.1600  -13.1600
            20  C8x C    11.9700  -13.8600
            21  C5a C    14.3500  -13.8600
            22  N1b N    15.6100  -13.1600
            23  C1b C    16.8000  -13.8600
            24  C1y C    17.9900  -13.1600
            25  O2x O    17.9900  -11.7600
            26  C1x C    19.2500  -11.0600
            27  C1x C    20.4400  -11.7600
            28  N1y N    20.4400  -13.1600
            29  C1x C    19.2500  -13.8600
            30  O2a O    14.3500  -11.0600
            31  C1b C    15.6100  -11.7600
            32  C1a C    16.8000  -11.0600
            33  X   Cl    9.5200  -13.8600
            34  N1a N     9.5200  -11.0600
            35  O5a O    14.3500  -15.2600
            36  C1b C    21.6300  -13.8600
            37  C8y C    22.8900  -13.1600
            38  C8x C    22.8900  -11.7600
            39  C8x C    24.0800  -11.0600
            40  C8y C    25.2700  -11.7600
            41  C8x C    25.2700  -13.1600
            42  C8x C    24.0800  -13.8600
            43  X   F    26.5300  -11.0600
            44  O0  O    14.7000  -18.8300
BOND        43
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 2
            9     6  10 1
            10    6  11 2
            11    7  12 1
            12    7  13 2
            13   15  16 2
            14   16  17 1
            15   17  18 2
            16   18  19 1
            17   19  20 2
            18   15  20 1
            19   19  21 1
            20   21  22 1
            21   22  23 1
            22   23  24 1
            23   24  25 1
            24   25  26 1
            25   26  27 1
            26   27  28 1
            27   28  29 1
            28   24  29 1
            29   18  30 1
            30   30  31 1
            31   31  32 1
            32   15  33 1
            33   16  34 1
            34   21  35 2
            35   28  36 1
            36   36  37 1
            37   37  38 2
            38   38  39 1
            39   39  40 2
            40   40  41 1
            41   41  42 2
            42   37  42 1
            43   40  43 1
BRACKET     1    12.3200  -19.8800   12.3200  -17.8500
            1    15.4700  -17.8500   15.4700  -19.8800
            1  2
 ORIGINAL  1   14
 REPEAT    1   44

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