KEGG   DRUG: Isoniazid sodium methanesulfonate hydrateHelp
Entry
D02002                      Drug                                   

Name
Isoniazid sodium methanesulfonate hydrate (JAN);
Isoniazid sodium methanesulfonate monohydrate;
Isoniazid sodium methanesulfonate;
IHMS;
Neoiscotin (TN)
Formula
C7H8N3O4S. Na. H2O
Exact mass
271.0239
Mol weight
271.2262
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antibacterial
 DG01966  Antitubercular
Neuropsychiatric agent
 DG01568  MAO inhibitor
  DG01519  Non-selective monoamine oxidase inhibitor
Cyp inhibitor
 DG01643  CYP2C9 inhibitor
 DG01522  CYP3A4 inhibitor
Cyp inducer
 DG01635  CYP3A4 inducer
Remark
Therapeutic category: 6222
ATC code: J04AC01
Chemical structure group: DG00642
Product (DG00642): D00346<JP/US> D02002<JP>
Efficacy
Antibacterial (tuberculostatic)
Comment
Hydrazide
Target
enoyl-[acyl-carrier-protein] reductase (NADH) [KO:K11611]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
    J04AC Hydrazides
     J04AC01 Isoniazid
      D02002  Isoniazid sodium methanesulfonate hydrate (JAN) <JP>
USP drug classification [BR:br08302]
 Antimycobacterials
  Antituberculars
   Isoniazid
    D02002  Isoniazid sodium methanesulfonate hydrate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   622  Tuberculosis preparations
    6222  Isoniazids
     D02002  Isoniazid sodium methanesulfonate hydrate (JAN)
BRITE hierarchy
Other DBs
PubChem: 7849064
DrugBank: DB00951
LigandBox: D02002
KCF data Show

ATOM        17
            1   N5x N     7.2800  -10.5700
            2   C8x C     7.2800  -11.9700
            3   C8x C     8.4924  -12.6700
            4   C8y C     9.7049  -11.9700
            5   C8x C     9.7049  -10.5700
            6   C8x C     8.4924   -9.8700
            7   C5a C    10.9424  -12.6700
            8   N1b N    12.1549  -11.9700
            9   N1b N    13.3673  -12.6700
            10  C1b C    14.5797  -11.9700
            11  S4a S    15.7922  -12.6700
            12  O1d O    17.0046  -11.9700 #-
            13  O5a O    10.9486  -14.0697
            14  O1d O    14.8022  -13.6599
            15  O1d O    16.7821  -13.6599
            16  Z   Na   18.8300  -11.9700 #+
            17  O0  O    20.1600  -13.8600
BOND        15
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13    7  13 2
            14   11  14 2
            15   11  15 2

» Japanese version   » Back

DBGET integrated database retrieval system