KEGG   DRUG: D02035Help
Entry
D02035                      Drug                                   

Name
Timiperone (JAN);
Tolopelon (TN)
Formula
C22H24FN3OS
Exact mass
397.1624
Mol weight
397.5089
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antipsychotic
Remark
Therapeutic category: 
Drug group: 
Comment
Butyropnenone derivatives
Target
dopamine D2-receptor antagonist [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Interaction
Drug interaction
Structure map
Butyrophenones
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   117  Psychotropics
    1179  Others
     D02035  Timiperone (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D2-receptor
     Timiperone
      D02035  Timiperone (JAN)
BRITE hierarchy
Other DBs
CAS: 
57648-21-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C8x C    24.1433  -18.9401
            2   C8y C    24.1433  -20.3393
            3   C8x C    25.3550  -21.0389
            4   C8x C    26.5668  -20.3393
            5   C8y C    26.5668  -18.9401
            6   C8x C    25.3550  -18.2405
            7   X   F    22.9317  -21.0389
            8   C5a C    27.7803  -18.2405
            9   C1b C    28.9920  -18.9401
            10  C1b C    30.2038  -18.2405
            11  C1b C    31.4155  -18.9401
            12  N1y N    32.6272  -18.2405
            13  C1x C    33.8422  -18.9420
            14  C1x C    35.0540  -18.2424
            15  C1y C    35.0540  -16.8432
            16  C1x C    33.8389  -16.1417
            17  C1x C    32.6273  -16.8413
            18  N4y N    36.2688  -16.1419
            19  C8y C    37.6022  -16.5563
            20  C8y C    38.4102  -15.4132
            21  N4x N    37.5727  -14.2915
            22  C8y C    36.2472  -14.7414
            23  O5a O    27.7808  -16.8413
            24  S0  S    35.1249  -13.9505
            25  C8x C    39.8102  -15.4132
            26  C8x C    40.5093  -16.6241
            27  C8x C    39.8291  -17.8019
            28  C8x C    38.4302  -17.8017
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     5   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   12  17 1
            19   15  18 1
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 1
            24   18  22 1
            25    8  23 2
            26   22  24 2
            27   20  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   28  19 1

» Japanese version   » Back

DBGET integrated database retrieval system