KEGG   DRUG: ClinprostHelp
Entry
D02048                      Drug                                   

Name
Clinprost (JAN/INN);
TEI 9090;
Arteron (TN)
Formula
C22H36O4
Exact mass
364.2614
Mol weight
364.5188
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01810  Prostacycline derivative
Other
 DG01961  Prostaglandin derivative
  DG01810  Prostacycline derivative
Unclassified
 DG02573  Prostanoid derivative
  DG01961  Prostaglandin derivative
   DG01810  Prostacycline derivative
Efficacy
Vasodilator (peripheral), Platelet aggregation inhibitor, Prostaglandin I2 receptor agonist
Comment
Prostacycline derivative
Target
PTGIR [HSA:5739] [KO:K04263]
  Pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Interaction
Drug interaction
Structure map
Eicosanoid receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostacyclin
    prostaglandin I2 receptor
     Clinprost
      D02048  Clinprost (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
88931-51-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C1x C     8.1900  -21.4200
            2   C1y C     9.0300  -22.5400
            3   C1y C    10.3600  -22.0500
            4   C1y C    10.3600  -20.6500
            5   C1y C     9.0300  -20.2300
            6   C2b C    11.6200  -22.7500
            7   C2b C    12.8100  -22.0500
            8   C1c C    14.0000  -22.6800
            9   C1b C    15.1900  -21.9800
            10  C1b C    16.4500  -22.6800
            11  C1b C    17.6400  -21.9800
            12  C1b C    18.8300  -22.6800
            13  C1a C    20.0900  -21.9800
            14  O1a O    14.0000  -24.0800
            15  O1a O     8.5400  -23.8700
            16  C1x C    11.2000  -19.5300
            17  C2y C    10.3600  -18.4100
            18  C2x C     9.0300  -18.8300
            19  C1b C    10.7800  -17.0800
            20  C1b C    11.9700  -16.3800
            21  C1b C    13.1600  -17.0800
            22  C1b C    14.3500  -16.3800
            23  C7a C    15.5400  -17.0800
            24  O7a O    16.7300  -16.3800
            25  O6a O    15.5400  -18.4800
            26  C1a C    17.9200  -17.0800
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     3   6 1 #Up
            7     6   7 2
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    8  14 1 #Up
            15    2  15 1 #Down
            16    4  16 1 #Down
            17   16  17 1
            18   17  18 2
            19    5  18 1 #Down
            20   17  19 1
            21   20  21 1
            22   20  19 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   23  25 2
            27   24  26 1

» Japanese version   » Back

DBGET integrated database retrieval system