 | | DRUG: Atropine sulfate | |
| Entry |
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| Name |
Atropine sulfate (JP18/USP);
Isopto Atropine (TN) |
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| Product |
ATROPEN AUTO-INJECTOR (Meridian Medical Technologies LLC), ATROPINE SULFATE (Accord Healthcare), ATROPINE SULFATE (Alcon Laboratories), ATROPINE SULFATE (Bausch & Lomb Americas), ATROPINE SULFATE (Bausch & Lomb Incorporated), ATROPINE SULFATE (Fresenius Kabi USA), ATROPINE SULFATE (HF Acquisition Co LLC), ATROPINE SULFATE (Henry Schein), ATROPINE SULFATE (Henry Schein), ATROPINE SULFATE (Hospira), ATROPINE SULFATE (Medical Purchasing Solutions), ATROPINE SULFATE (Medical Purchasing Solutions), ATROPINE SULFATE (Medical Purchasing Solutions), ISOPTO ATROPINE (Alcon Laboratories) |
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| Generic |
ATROPINE (A-S Medication Solutions), ATROPINE (Akorn), ATROPINE (Amneal Pharmaceuticals NY LLC), ATROPINE (Apotex Corp.), ATROPINE SULFATE (A-S Medication Solutions), ATROPINE SULFATE (Accord Healthcare), ATROPINE SULFATE (Accord Healthcare), ATROPINE SULFATE (American Regent), ATROPINE SULFATE (Amneal Pharmaceuticals LLC), ATROPINE SULFATE (HF Acquisition Co LLC), ATROPINE SULFATE (HF Acquisition Co LLC), ATROPINE SULFATE (HF Acquisition Co LLC), ATROPINE SULFATE (HF Acquisition Co LLC), ATROPINE SULFATE (Henry Schein), ATROPINE SULFATE (Hikma Pharmaceuticals USA), ATROPINE SULFATE (International Medication Systems), ATROPINE SULFATE (Lifestar Pharma LLC), ATROPINE SULFATE (Medefil), ATROPINE SULFATE (Medical Purchasing Solutions), ATROPINE SULFATE (Medical Purchasing Solutions), ATROPINE SULFATE (Medical Purchasing Solutions), ATROPINE SULFATE (Medical Purchasing Solutions), ATROPINE SULFATE (REMEDYREPACK) |
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| Formula |
(C17H23NO3)2. H2SO4. H2O
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| Exact mass |
694.3135
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| Mol weight |
694.8326
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
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| Remark |
| Product (DG00052): | D02069<JP/US> |
| Product (mixture): | D00301<US> D02128<US> D09186<JP> |
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| Efficacy |
Antispasmodic, Mydriatic, Muscarinic acetylcholine receptor antagonist |
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| Comment |
Tropane derivative
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03B BELLADONNA AND DERIVATIVES, PLAIN
A03BA Belladonna alkaloids, tertiary amines
A03BA01 Atropine
D02069 Atropine sulfate (JP18/USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01F MYDRIATICS AND CYCLOPLEGICS
S01FA Anticholinergics
S01FA01 Atropine
D02069 Atropine sulfate (JP18/USP) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
124 Antispasmodics
1242 Atropines
D02069 Atropine sulfate (JP18/USP)
13 Agents affecting sensory organs
131 Ophthalmic agents
1311 Mydriatic agents
D02069 Atropine sulfate (JP18/USP)
1318 Alkaloids
D02069 Atropine sulfate (JP18/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00052 Atropine
D02069 Atropine sulfate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D02069 Atropine sulfate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02069 Atropine sulfate hydrate
D02069 Atropine sulfate injection
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00052 Atropine
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| Other DBs |
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| KCF data |
ATOM 48
1 S4a S 30.5665 -18.3867
2 O1d O 30.5665 -16.9867
3 O1d O 30.5665 -19.7867
4 O1d O 31.9665 -18.3867
5 O1d O 29.1666 -18.3867
6 O0 O 36.2599 -18.3400
7 C1x C 15.7738 -18.5308
8 C1x C 16.1019 -17.3591
9 C1y C 16.9455 -18.2496
10 C1y C 17.2736 -17.0779
11 N1y N 16.0082 -15.7656
12 C1x C 18.8202 -18.2496
13 C1x C 18.5390 -17.0779
14 C1y C 19.8513 -18.8120
15 O7a O 20.9293 -19.7025
16 C7a C 22.1479 -19.7025
17 C1c C 22.7572 -18.6245
18 O6a O 22.7572 -20.8273
19 C8y C 23.9758 -18.6245
20 C1b C 22.1479 -17.5934
21 O1a O 22.7572 -16.5155
22 C8x C 24.6820 -19.8482
23 C8x C 26.0820 -19.8485
24 C8x C 26.7822 -18.6362
25 C8x C 26.0761 -17.4125
26 C8x C 24.6761 -17.4122
27 C1a C 15.2591 -14.5814
28 C1x C 15.7738 -18.5308
29 C1x C 16.1019 -17.3591
30 C1y C 17.2736 -17.0779
31 C1x C 18.5390 -17.0779
32 C1y C 19.8513 -18.8120
33 C1x C 18.8202 -18.2496
34 C1y C 16.9455 -18.2496
35 N1y N 16.0082 -15.7656
36 C1a C 15.2591 -14.5814
37 O7a O 20.9293 -19.7025
38 C7a C 22.1479 -19.7025
39 C1c C 22.7572 -18.6245
40 C8y C 23.9758 -18.6245
41 C8x C 24.6820 -19.8482
42 C8x C 26.0820 -19.8485
43 C8x C 26.7822 -18.6362
44 C8x C 26.0761 -17.4125
45 C8x C 24.6761 -17.4122
46 C1b C 22.1479 -17.5934
47 O1a O 22.7572 -16.5155
48 O6a O 22.7572 -20.8273
BOND 50
1 1 2 2
2 1 3 2
3 1 4 1
4 1 5 1
5 7 8 1
6 7 9 1
7 8 10 1
8 9 11 1
9 9 12 1
10 10 13 1
11 12 14 1
12 14 15 1 #Down
13 15 16 1
14 16 17 1
15 16 18 2
16 17 19 1
17 17 20 1
18 20 21 1
19 10 11 1
20 13 14 1
21 19 22 2
22 22 23 1
23 23 24 2
24 24 25 1
25 25 26 2
26 19 26 1
27 11 27 1
28 28 29 1
29 28 34 1
30 29 30 1
31 34 35 1
32 34 33 1
33 30 31 1
34 33 32 1
35 32 37 1 #Down
36 37 38 1
37 38 39 1
38 38 48 2
39 39 40 1
40 39 46 1
41 46 47 1
42 30 35 1
43 31 32 1
44 40 41 2
45 41 42 1
46 42 43 2
47 43 44 1
48 44 45 2
49 40 45 1
50 35 36 1
BRACKET 1 13.2300 -21.3500 13.2300 -13.7200
1 27.0900 -13.7200 27.0900 -21.3500
1 2
ORIGINAL 1 7 8 10 13 14 12 9 11 29 22 15 16 17 19 24 25
1 26 27 28 20 21 18 23
REPEAT 1 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45
1 46 47 48 49 50 51 52
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