KEGG   DRUG: D02070Help
Entry
D02070                      Drug                                   

Name
Homatropine methylbromide (USP);
Equipin (TN)
Formula
C17H24NO3. Br
Exact mass
369.094
Mol weight
370.2814
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergic
Remark
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA05 Homatropine
      D02070  Homatropine methylbromide (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Homatropine
      D02070  Homatropine methylbromide (USP)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D02070  Homatropine methylbromide (USP)
BRITE hierarchy
Other DBs
CAS: 
80-49-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C1x C    26.2738  -16.4308
            2   C1x C    26.6019  -15.2591
            3   C1y C    27.4455  -16.1496
            4   C1y C    27.7736  -14.9779
            5   N2y N    26.5082  -13.6656 #+
            6   C1x C    29.3202  -16.1496
            7   C1x C    29.0390  -14.9779
            8   C1y C    30.3513  -16.7120
            9   O7a O    31.4293  -17.6025
            10  C7a C    32.6479  -17.6025
            11  C1c C    33.2572  -16.5245
            12  O6a O    33.2572  -18.7273
            13  C8y C    34.4758  -16.5245
            14  O1a O    32.6479  -15.4934
            15  C8x C    35.1820  -17.7482
            16  C8x C    36.5820  -17.7485
            17  C8x C    37.2822  -16.5362
            18  C8x C    36.5761  -15.3125
            19  C8x C    35.1761  -15.3122
            20  C1a C    25.7591  -12.4814
            21  C1a C    25.2789  -14.2783
            22  X   Br   30.3100  -12.6700 #-
BOND        23
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1 #Down
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 1
            13   11  14 1
            14    4   5 1
            15    7   8 1
            16   13  15 2
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   18  19 2
            21   13  19 1
            22    5  20 1
            23    5  21 1

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