KEGG   DRUG: D02082Help
Entry
D02082                      Drug                                   

Name
Eprosartan mesylate (USAN);
Teveten (TN)
Product
  Generic
Formula
C23H24N2O4S. CH4SO3
Exact mass
520.1338
Mol weight
520.6183
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensice
Remark
ATC code: 
Drug group: 
Target
angiotensin II receptor type 1 (AT1) antagonist [HSA:185] [KO:K04166]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Structure map
Angiotensin receptor and endothelin receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09C ANGIOTENSIN II ANTAGONISTS, PLAIN
    C09CA Angiotensin II antagonists, plain
     C09CA02 Eprosartan
      D02082  Eprosartan mesylate (USAN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Angiotensin II Receptor Antagonists
   Eprosartan
    D02082  Eprosartan mesylate (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Angiotensin
    angiotensin II stimulates angiotensin subtype 1 (AT1) receptor
     Eprosartan
      D02082  Eprosartan mesylate (USAN)
BRITE hierarchy
Other DBs
CAS: 
144143-96-4
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        35
            1   S4a S    30.8361  -23.7268
            2   O1d O    30.8361  -22.3207
            3   O1d O    30.8361  -25.1329
            4   O1d O    32.2422  -23.7268
            5   C1a C    29.4300  -23.7268
            6   C8x C    17.2200  -21.0700
            7   C8y C    17.2200  -22.4700
            8   C8x C    18.4100  -23.2400
            9   C8x C    19.6000  -22.4700
            10  C8y C    19.6000  -21.0700
            11  C8x C    18.4100  -20.3700
            12  C1b C    20.8600  -20.3700
            13  N4y N    22.0500  -21.0700
            14  C8y C    22.5400  -22.4000
            15  C8x C    23.9400  -22.4000
            16  N5x N    24.3600  -21.0700
            17  C8y C    23.2400  -20.2300
            18  C6a C    15.9600  -23.2400
            19  O6a O    14.7700  -22.5400
            20  O6a O    15.9600  -24.6400
            21  C1b C    23.2400  -18.8300
            22  C1b C    24.4300  -18.1300
            23  C1b C    25.6900  -18.8300
            24  C1a C    26.8800  -18.1300
            25  C2b C    21.8400  -23.6600
            26  C2c C    22.5400  -24.8500
            27  C1b C    23.9400  -24.8500
            28  C6a C    21.8400  -26.0400
            29  O6a O    20.4400  -26.0400
            30  O6a O    22.5400  -27.2300
            31  C8y C    24.6400  -26.0400
            32  C8x C    24.2900  -27.3700
            33  C8x C    25.4100  -28.1400
            34  C8x C    26.4600  -27.3000
            35  S2x S    26.0400  -25.9700
BOND        36
            1     1   2 2
            2     1   3 2
            3     1   4 1
            4     1   5 1
            5     6   7 2
            6     7   8 1
            7     8   9 2
            8     9  10 1
            9    10  11 2
            10    6  11 1
            11   10  12 1
            12   12  13 1
            13   13  14 1
            14   14  15 2
            15   15  16 1
            16   16  17 2
            17   13  17 1
            18    7  18 1
            19   18  19 1
            20   18  20 2
            21   17  21 1
            22   21  22 1
            23   22  23 1
            24   23  24 1
            25   14  25 1
            26   25  26 2
            27   26  27 1
            28   26  28 1
            29   28  29 1
            30   28  30 2
            31   27  31 1
            32   31  32 2
            33   32  33 1
            34   33  34 2
            35   34  35 1
            36   31  35 1

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