KEGG   DRUG: D02109Help
Entry
D02109                      Drug                                   

Name
dl-Methylephedrine hydrochloride (JP16);
Methy-F (TN)
Formula
C11H17NO. HCl
Exact mass
215.1077
Mol weight
215.7197
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator [DS:H00079]
Remark
Same as: 
Therapeutic category: 
Target
alpha1-adrenergic receptor agonist [HSA:148 147 146] [KO:K04135 K04136 K04137];
alpha2-adrenergic receptor agonist [HSA:150 151 152] [KO:K04138 K04139 K04140];
beta1-adrenergic receptor agonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor agonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   222  Antitussives
    2221  Ephedrines and Ephedra herbs
     D02109  dl-Methylephedrine hydrochloride (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
     Methylephedrine
      D02109  dl-Methylephedrine hydrochloride (JP16)
    alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140]
     Methylephedrine
      D02109  dl-Methylephedrine hydrochloride (JP16)
    beta1-adrenergic receptor [HSA:153] [KO:K04141]
     Methylephedrine
      D02109  dl-Methylephedrine hydrochloride (JP16)
    beta2-adrenergic receptor [HSA:154] [KO:K04142]
     Methylephedrine
      D02109  dl-Methylephedrine hydrochloride (JP16)
    beta3-adrenergic receptor [HSA:155] [KO:K04143]
     Methylephedrine
      D02109  dl-Methylephedrine hydrochloride (JP16)
BRITE hierarchy
Other DBs
CAS: 
18760-80-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   C8x C    27.6287  -17.1735
            2   C8x C    27.6287  -18.5731
            3   C8x C    28.8416  -19.2728
            4   C8x C    30.0545  -18.5731
            5   C8y C    30.0545  -17.1735
            6   C8x C    28.8416  -16.4738
            7   C1c C    31.2674  -16.4738
            8   C1c C    32.4804  -17.1735
            9   N1c N    33.6933  -16.4738
            10  C1a C    34.9062  -17.1735
            11  C1a C    32.4804  -18.5731
            12  O1a O    31.2674  -15.0743
            13  C1a C    33.6933  -15.0743
            14  X   Cl   39.4336  -16.9402
BOND        13
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    8  11 1
            12    7  12 1
            13    9  13 1

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